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Literature DB >> 11970890

Reaching a genetic and molecular understanding of skeletal development.

Abstract

In the last ten years, we have made considerable progress in our genetic and molecular understanding of all aspects of skeletal development, chondrogenesis, joint formation, and osteogenesis. This review addresses the role of the principal growth factors and transcription factors affecting these different processes and presents, in several cases, the genetic cascade leading to cell differentiation.

Keywords: Non-programmatic

Mesh：

Year: 2002 PMID： 11970890 DOI： 10.1016/s1534-5807(02)00157-0

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

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Cited

465 in total

1. A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q13-q21.

Authors: Simeon A Boyadjiev; Cristina M Justice; Wafaa Eyaid; Victor A McKusick; Ralph S Lachman; Arnab B Chowdry; Monzer Jabak; Johan Zwaan; Alexander F Wilson; Ethylin Wang Jabs
Journal: Hum Genet Date: 2003-04-03 Impact factor: 4.132

2. Wdr5 is required for chick skeletal development.

Authors: Shimei Zhu; Eric D Zhu; Sylvain Provot; Francesca Gori
Journal: J Bone Miner Res Date: 2010-11 Impact factor: 6.741

3. A microRNA expression signature of osteoclastogenesis.

Authors: Toshifumi Sugatani; Jean Vacher; Keith A Hruska
Journal: Blood Date: 2011-01-27 Impact factor: 22.113

Review 4. A bit of give and take: the relationship between the extracellular matrix and the developing chondrocyte.

Authors: Danielle J Behonick; Zena Werb
Journal: Mech Dev Date: 2003-11 Impact factor: 1.882

5. Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.

Authors: Christa Maes; Ingrid Stockmans; Karen Moermans; Riet Van Looveren; Nico Smets; Peter Carmeliet; Roger Bouillon; Geert Carmeliet
Journal: J Clin Invest Date: 2004-01 Impact factor: 14.808

10. N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.

Authors: Eric Haÿ; Emmanuel Laplantine; Valérie Geoffroy; Monique Frain; Thomas Kohler; Ralph Müller; Pierre J Marie
Journal: Mol Cell Biol Date: 2008-12-15 Impact factor: 4.272

Reaching a genetic and molecular understanding of skeletal development.

1. A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q13-q21.

2. Wdr5 is required for chick skeletal development.

3. A microRNA expression signature of osteoclastogenesis.

Review 4. A bit of give and take: the relationship between the extracellular matrix and the developing chondrocyte.

5. Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.

6. Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.

Review 7. Matrix remodeling during endochondral ossification.

Review 8. MicroRNAs and their roles in osteoclast differentiation.

9. Tendons and muscles of the mouse forelimb during embryonic development.

10. N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.