| Literature DB >> 11968120 |
Yasushi Ishihama1, Hiroyuki Katayama, Naoki Asakawa, Yoshiya Oda.
Abstract
Tapered stainless steel spray tips for sheathless microelectrospray ionization (microESI) have been developed. The fabrication procedure for the tapered stainless steel tips was optimized using an electropolishing technique followed by removal of the burr. Using the tip as the microESI emitter, a stable ESI spray was obtained at a flow rate of 20 nL/min. The sensitivity of the microESI system was almost two orders greater than that of the conventional ion spray system. The tip was highly stable, and was successfully used for over 1000 h. Moreover, these stainless steel tips were suitable for use with sheathless capillary electrophoresis/mass spectrometry (CE/MS) and capillary liquid chromatography/mass spectrometry (LC/MS) for routine analysis in proteomic and pharmaceutical applications. Copyright 2002 John Wiley & Sons, Ltd.Entities:
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Year: 2002 PMID: 11968120 DOI: 10.1002/rcm.647
Source DB: PubMed Journal: Rapid Commun Mass Spectrom ISSN: 0951-4198 Impact factor: 2.419