Literature DB >> 11956539

Octogenarian free flap reconstruction: complications and cost of therapy.

Keith E Blackwell1, Babak Azizzadeh, Carlos Ayala, Jeffrey D Rawnsley.   

Abstract

OBJECTIVE: The study goal was to document the reliability, incidence of complications, and cost of therapy for patients older than 80 years who undergo microvascular head and neck reconstruction. PATIENTS AND METHODS: Thirteen octogenarians underwent free flap reconstruction of defects resulting from the treatment of head and neck cancer at an academic tertiary care medical center. The incidence of medical and reconstructive complications and the cost of hospitalization were compared with those for 99 younger patients who were treated during the same time period.
RESULTS: There were no cases of free flap failure or significant reconstructive complications in the octogenarians. The incidence of medical complications was 62% in the octogenarians and 15% in the younger patients. The average cost of therapy was $54,702 per octogenarian patient compared with $30,397 per younger patient. The increased incidence of medical complications and increased cost arose primarily from an increased severity of preoperative systemic illness in the octogenarians. However, controlling for comorbidity did not eliminate the discrepancy in medical complications between the octogenarians and the younger patients.
CONCLUSIONS: Although microvascular head and neck reconstruction in the elderly is very reliable, the incidence of medical complications and the cost of therapy are significantly increased in octogenarians.

Entities:  

Mesh:

Year:  2002        PMID: 11956539     DOI: 10.1067/mhn.2002.122704

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  13 in total

Review 1.  Economic burden of head and neck cancer. A literature review.

Authors:  Jennifer M Lee; Marco Turini; Marc F Botteman; Jennifer M Stephens; Chris L Pashos
Journal:  Eur J Health Econ       Date:  2004-02

2.  Utility and relevance of modified lateral trapezius myocutaneous flap as a locoregional reconstructive option for medium-sized ablative defects in head and neck cancer-our experience.

Authors:  Abhishek Singh; Mudit Agarwal; Naveen Singh; Harit Chaturvedi; Manikandan Venkatasubramaniyan; Anshu Chopra
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-04-08       Impact factor: 2.503

3.  Analysis of outcome for elderly patients after microvascular flap surgery: a monocentric retrospective cohort study.

Authors:  Henning Hanken; Evgeny Barsukov; Friedemann Göhler; Susanne Sehner; Ralf Smeets; Benedicta Beck-Broichsitter; Max Heiland; Kilian Kreutzer; Alexander Gröbe
Journal:  Clin Oral Investig       Date:  2019-05-08       Impact factor: 3.573

4.  Pedicled Flap vs. Free Flap Reconstruction in Head and Neck Cancers: Clinical Outcome Analysis from a Single Surgical Team.

Authors:  Rakesh Katna; Farhana Girkar; Debayan Tarafdar; Bharat Bhosale; Shambhavi Singh; Suyash Agarwal; Akshay Deshpande; Nikhil Kalyani
Journal:  Indian J Surg Oncol       Date:  2021-05-17

5.  Defining the critical-sized defect in a rat segmental mandibulectomy model.

Authors:  Adam S DeConde; Matthew K Lee; Douglas Sidell; Tara Aghaloo; Min Lee; Sotirios Tetradis; Kyle Low; David Elashoff; Tristan Grogan; Ali R Sepahdari; Maie St John
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2014-01       Impact factor: 6.223

6.  Head and neck reconstruction with free flaps: a report on 213 cases.

Authors:  Olivier Dassonville; Gilles Poissonnet; Emmanuel Chamorey; Jacques Vallicioni; François Demard; Joseph Santini; Mayeul Lecoq; Sophie Converset; Pouya Mahdyoun; Alexandre Bozec
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-08-10       Impact factor: 2.503

7.  Assessment of Hedgehog Signaling Pathway Activation for Craniofacial Bone Regeneration in a Critical-Sized Rat Mandibular Defect.

Authors:  Matthew Q Miller; Logan F McColl; Michael R Arul; Jonathan Nip; Vedavathi Madhu; Gina Beck; Kishan Mathur; Vashaana Sahadeo; Jason R Kerrigan; Stephen S Park; J Jared Christophel; Abhijit S Dighe; Sangamesh G Kumbar; Quanjun Cui
Journal:  JAMA Facial Plast Surg       Date:  2019-03-01       Impact factor: 4.611

8.  Impact of comprehensive geriatric assessment on survival, function, and nutritional status in elderly patients with head and neck cancer: protocol for a multicentre randomised controlled trial (EGeSOR).

Authors:  Lydia Brugel; Marie Laurent; Philippe Caillet; Anne Radenne; Isabelle Durand-Zaleski; Michel Martin; Melany Baron; Héloïse de Kermadec; Sylvie Bastuji-Garin; Florence Canouï-Poitrine; Elena Paillaud
Journal:  BMC Cancer       Date:  2014-06-13       Impact factor: 4.430

Review 9.  The economic burden of head and neck cancer: a systematic literature review.

Authors:  Erika Wissinger; Ingolf Griebsch; Juliane Lungershausen; Talia Foster; Chris L Pashos
Journal:  Pharmacoeconomics       Date:  2014-09       Impact factor: 4.981

10.  Clinical Factors Associated With Reoperation and Prolonged Length of Stay in Free Tissue Transfer to Oncologic Head and Neck Defects.

Authors:  William W Thomas; Jason Brant; Jinbo Chen; Orly Coblens; John P Fischer; Jason G Newman; Ara A Chalian; Rabie M Shanti; Steven B Cannady
Journal:  JAMA Facial Plast Surg       Date:  2018-03-01       Impact factor: 4.611

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