| Literature DB >> 11955439 |
Abstract
When complexed with the catalytic subunit of DNA-dependent protein kinase (DNA-PK(cs)), the recently discovered dsDNA break repair protein named Artemis acquires the ability to open hairpin DNA molecules in vitro. Both genetic and biochemical data point toward a physiological role for this complex as the elusive hairpin-opening activity in V(D)J recombination.Entities:
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Year: 2002 PMID： 11955439 DOI： 10.1016/s0092-8674(02)00694-3
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582