Literature DB >> 11953415

Identification and functional analysis of an immunoreactive DsbA-like thio-disulfide oxidoreductase of Ehrlichia spp.

Jere W McBride1, Lucy M Ndip, Vsevolod L Popov, David H Walker.   

Abstract

Novel homologous DsbA-like disulfide bond formation (Dsb) proteins of Ehrlichia chaffeensis and Ehrlichia canis were identified which restored DsbA activity in complemented Escherichia coli dsbA mutants. Recombinant Ehrlichia Dsb (eDsb) proteins were recognized by sera from E. canis-infected dogs but not from E. chaffeensis-infected patients. The eDsb proteins were observed primarily in the periplasm of E. chaffeensis and E. canis.

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Year:  2002        PMID: 11953415      PMCID: PMC127935          DOI: 10.1128/IAI.70.5.2700-2703.2002

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  17 in total

1.  Characterization of the complete transcriptionally active ehrlichia chaffeensis 28 kDa outer membrane protein multigene family.

Authors:  X Yu; J W McBride; X Zhang; D H Walker
Journal:  Gene       Date:  2000-05-02       Impact factor: 3.688

2.  Immunodiagnosis of Ehrlichia canis infection with recombinant proteins.

Authors:  J W McBride; R E Corstvet; E B Breitschwerdt; D H Walker
Journal:  J Clin Microbiol       Date:  2001-01       Impact factor: 5.948

3.  Ultrastructural differentiation of the genogroups in the genus Ehrlichia.

Authors:  V L Popov; V C Han; S M Chen; J S Dumler; H M Feng; T G Andreadis; R B Tesh; D H Walker
Journal:  J Med Microbiol       Date:  1998-03       Impact factor: 2.472

4.  The role of thioredoxin in filamentous phage assembly. Construction, isolation, and characterization of mutant thioredoxins.

Authors:  M Russel; P Model
Journal:  J Biol Chem       Date:  1986-11-15       Impact factor: 5.157

5.  Identification of a protein required for disulfide bond formation in vivo.

Authors:  J C Bardwell; K McGovern; J Beckwith
Journal:  Cell       Date:  1991-11-01       Impact factor: 41.582

6.  Cloning and sequencing of Coxiella burnetii outer membrane protein gene com1.

Authors:  L R Hendrix; L P Mallavia; J E Samuel
Journal:  Infect Immun       Date:  1993-02       Impact factor: 3.441

7.  Mutants in disulfide bond formation that disrupt flagellar assembly in Escherichia coli.

Authors:  F E Dailey; H C Berg
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-01       Impact factor: 11.205

8.  Intermolecular relationships of major surface proteins of Anaplasma marginale.

Authors:  M C Vidotto; T C McGuire; T F McElwain; G H Palmer; D P Knowles
Journal:  Infect Immun       Date:  1994-07       Impact factor: 3.441

9.  Identification and characterization of an Escherichia coli gene required for the formation of correctly folded alkaline phosphatase, a periplasmic enzyme.

Authors:  S Kamitani; Y Akiyama; K Ito
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

10.  The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation.

Authors:  D Missiakas; C Georgopoulos; S Raina
Journal:  EMBO J       Date:  1994-04-15       Impact factor: 11.598

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  19 in total

1.  Differentially expressed and secreted major immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis elicit early antibody responses to epitopes on glycosylated tandem repeats.

Authors:  C Kuyler Doyle; Kimberly A Nethery; Vsevolod L Popov; Jere W McBride
Journal:  Infect Immun       Date:  2006-01       Impact factor: 3.441

2.  Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats.

Authors:  Jere W McBride; Xiaofeng Zhang; Abdul Wakeel; Jeeba A Kuriakose
Journal:  Infect Immun       Date:  2011-05-23       Impact factor: 3.441

3.  Ehrlichia chaffeensis TRP120 binds a G+C-rich motif in host cell DNA and exhibits eukaryotic transcriptional activator function.

Authors:  Bing Zhu; Jeeba A Kuriakose; Tian Luo; Efren Ballesteros; Sharu Gupta; Yuriy Fofanov; Jere W McBride
Journal:  Infect Immun       Date:  2011-08-22       Impact factor: 3.441

4.  The genome of the obligately intracellular bacterium Ehrlichia canis reveals themes of complex membrane structure and immune evasion strategies.

Authors:  K Mavromatis; C Kuyler Doyle; A Lykidis; N Ivanova; M P Francino; P Chain; M Shin; S Malfatti; F Larimer; A Copeland; J C Detter; M Land; P M Richardson; X J Yu; D H Walker; J W McBride; N C Kyrpides
Journal:  J Bacteriol       Date:  2006-06       Impact factor: 3.490

5.  Detection of medically important Ehrlichia by quantitative multicolor TaqMan real-time polymerase chain reaction of the dsb gene.

Authors:  C Kuyler Doyle; Marcelo B Labruna; Edward B Breitschwerdt; Yi-Wei Tang; Richard E Corstvet; Barbara C Hegarty; Karen C Bloch; Ping Li; David H Walker; Jere W McBride
Journal:  J Mol Diagn       Date:  2005-10       Impact factor: 5.568

6.  Identification of a glycosylated Ehrlichia canis 19-kilodalton major immunoreactive protein with a species-specific serine-rich glycopeptide epitope.

Authors:  Jere W McBride; C Kuyler Doyle; Xiaofeng Zhang; Ana Maria Cardenas; Vsevolod L Popov; Kimberly A Nethery; Michael E Woods
Journal:  Infect Immun       Date:  2006-11-06       Impact factor: 3.441

7.  Nuclear translocated Ehrlichia chaffeensis ankyrin protein interacts with a specific adenine-rich motif of host promoter and intronic Alu elements.

Authors:  Bing Zhu; Kimberly A Nethery; Jeeba A Kuriakose; Abdul Wakeel; Xiaofeng Zhang; Jere W McBride
Journal:  Infect Immun       Date:  2009-08-03       Impact factor: 3.441

8.  Surface-exposed proteins of Ehrlichia chaffeensis.

Authors:  Yan Ge; Yasuko Rikihisa
Journal:  Infect Immun       Date:  2007-05-21       Impact factor: 3.441

9.  Ehrlichia canis gp200 contains dominant species-specific antibody epitopes in terminal acidic domains.

Authors:  Kimberly A Nethery; C Kuyler Doyle; Xiaofeng Zhang; Jere W McBride
Journal:  Infect Immun       Date:  2007-08-06       Impact factor: 3.441

10.  Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.

Authors:  Nagaraja R Thirumalapura; Patricia A Crocquet-Valdes; Tais B Saito; Sunil Thomas; Jere W McBride; David H Walker
Journal:  Vaccine       Date:  2013-10-19       Impact factor: 3.641

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