Literature DB >> 11953330

The genetic jigsaw of inflammatory bowel disease.

D A Watts1, J Satsangi.   

Abstract

Following a prolonged period of relative inertia, real progress has been made in the past few years in understanding the pathogenesis of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis. Clinical experience, epidemiological studies, and molecular genetics have provided strong evidence that both genetic and environmental factors are important in disease pathogenesis, and gene-environmental interaction determines disease susceptibility and behaviour.

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Year:  2002        PMID： 11953330      PMCID： PMC1867682          DOI： 10.1136/gut.50.suppl_3.iii31

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  43 in total

1.  HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis.

Authors:  P C Stokkers; P H Reitsma; G N Tytgat; S J van Deventer
Journal:  Gut       Date:  1999-09       Impact factor: 23.059

2.  High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12.

Authors:  R H Duerr; M M Barmada; L Zhang; R Pfützer; D E Weeks
Journal:  Am J Hum Genet       Date:  2000-04-03       Impact factor: 11.025

3.  ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease.

Authors:  K D Taylor; S E Plevy; H Yang; C J Landers; M J Barry; J I Rotter; S R Targan
Journal:  Gastroenterology       Date:  2001-05       Impact factor: 22.682

4.  A second-generation linkage map of the human genome.

Authors:  J Weissenbach; G Gyapay; C Dib; A Vignal; J Morissette; P Millasseau; G Vaysseix; M Lathrop
Journal:  Nature       Date:  1992-10-29       Impact factor: 49.962

Review 5.  Aetiology and natural history of primary sclerosing cholangitis--a decade of progress?

Authors:  R W Chapman
Journal:  Gut       Date:  1991-12       Impact factor: 23.059

6.  Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease.

Authors:  C Cuffari; S Hunt; T Bayless
Journal:  Gut       Date:  2001-05       Impact factor: 23.059

Review 7.  Review article: the genetics of inflammatory bowel disease.

Authors:  T Ahmad; J Satsangi; D McGovern; M Bunce; D P Jewell
Journal:  Aliment Pharmacol Ther       Date:  2001-06       Impact factor: 8.171

8.  Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.

Authors:  J P Hugot; M Chamaillard; H Zouali; S Lesage; J P Cézard; J Belaiche; S Almer; C Tysk; C A O'Morain; M Gassull; V Binder; Y Finkel; A Cortot; R Modigliani; P Laurent-Puig; C Gower-Rousseau; J Macry; J F Colombel; M Sahbatou; G Thomas
Journal:  Nature       Date:  2001-05-31       Impact factor: 49.962

9.  A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.

Authors:  Y Ogura; D K Bonen; N Inohara; D L Nicolae; F F Chen; R Ramos; H Britton; T Moran; R Karaliuskas; R H Duerr; J P Achkar; S R Brant; T M Bayless; B S Kirschner; S B Hanauer; G Nuñez; J H Cho
Journal:  Nature       Date:  2001-05-31       Impact factor: 49.962

10.  Investigation of inheritance of chronic inflammatory bowel diseases by complex segregation analysis.

Authors:  M Orholm; L Iselius; T I Sørensen; P Munkholm; E Langholz; V Binder
Journal:  BMJ       Date:  1993-01-02
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  17 in total

1.  Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

Authors:  Muddassar M Mirza; Sheila A Fisher; Kathy King; Andrew P Cuthbert; Jochen Hampe; Jeremy Sanderson; John Mansfield; Peter Donaldson; Andrew J S Macpherson; Alastair Forbes; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Journal:  Am J Hum Genet       Date:  2003-03-03       Impact factor: 11.025

2.  Role of Salmonella enterica exposure in Chilean Crohn's disease patients.

Authors:  Manuel Alvarez-Lobos; Daniela P Pizarro; Christian E Palavecino; Abner Espinoza; Valentina P Sebastián; Juan C Alvarado; Patricio Ibañez; Carlos Quintana; Orlando Díaz; Alexis M Kalergis; Susan M Bueno
Journal:  World J Gastroenterol       Date:  2013-09-21       Impact factor: 5.742

3.  Consistent across-tissue signatures of differential gene expression in Crohn's disease.

Authors:  Austin L Hughes
Journal:  Immunogenetics       Date:  2005-11-08       Impact factor: 2.846

4.  Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese.

Authors:  Haruhisa Machida; Kazuhiro Tsukamoto; Chun-Yang Wen; Yukiko Narumi; Saburou Shikuwa; Hajime Isomoto; Fuminao Takeshima; Yohei Mizuta; Norio Niikawa; Ikuo Murata; Shigeru Kohno
Journal:  World J Gastroenterol       Date:  2005-07-21       Impact factor: 5.742

5.  Haplotype of prostaglandin synthase 2/cyclooxygenase 2 is involved in the susceptibility to inflammatory bowel disease.

Authors:  David-G Cox; J-Bart-A Crusius; Petra-H-M Peeters; H-Bas Bueno-de-Mesquita; A-Salvador Pena; Federico Canzian
Journal:  World J Gastroenterol       Date:  2005-10-14       Impact factor: 5.742

6.  Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.

Authors:  Haruhisa Machida; Kazuhiro Tsukamoto; Chun-Yang Wen; Saburou Shikuwa; Hajime Isomoto; Yohei Mizuta; Fuminao Takeshima; Kunihiko Murase; Naomichi Matsumoto; Ikuo Murata; Shigeru Kohno; Chen-Yang Wen
Journal:  World J Gastroenterol       Date:  2005-08-21       Impact factor: 5.742

Review 7.  The complexity and challenges of genetic counseling and testing for inflammatory bowel disease.

Authors:  Shelly A Cummings; David T Rubin
Journal:  J Genet Couns       Date:  2006-12       Impact factor: 2.537

8.  Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis.

Authors:  D Franchimont; S Vermeire; H El Housni; M Pierik; K Van Steen; T Gustot; E Quertinmont; M Abramowicz; A Van Gossum; J Devière; P Rutgeerts
Journal:  Gut       Date:  2004-07       Impact factor: 23.059

9.  Anti-Saccharomyces cerevisiae antibodies (ASCA) in Crohn's disease are associated with disease severity but not NOD2/CARD15 mutations.

Authors:  L J Walker; M C Aldhous; H E Drummond; B R K Smith; E R Nimmo; I D R Arnott; J Satsangi
Journal:  Clin Exp Immunol       Date:  2004-03       Impact factor: 4.330

Review 10.  The pathogenesis of inflammatory bowel disease: translational implications for clinicians.

Authors:  Maria T Abreu
Journal:  Curr Gastroenterol Rep       Date:  2002-12
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