Literature DB >> 11950591

The role of Rho GTPases and associated kinases in regulating neurite outgrowth.

Margareta Nikolic1.   

Abstract

Neurones are highly specialised cells that can extend over great distances, enabling the complex networking of the nervous system. We are beginning to understand in detail the molecular mechanisms that control the shape of neurones during development. One family of proteins that are clearly essential are the Rho GTPases which have a pivotal role in regulating the actin cytoskeleton in all cell types. The Rho GTPases are responsible for the activation and downregulation of many downstream kinases. This review discusses individual kinases that are regulated by three members of the Rho GTPases, Rac, Rho and Cdc42 and their function during neurite outgrowth and remodelling.

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Year:  2002        PMID： 11950591     DOI： 10.1016/s1357-2725(01)00167-4

Source DB:  PubMed          Journal:  Int J Biochem Cell Biol        ISSN： 1357-2725            Impact factor:   5.085


  46 in total

Review 1.  Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes.

Authors:  Aleksandar Ivetic; Anne J Ridley
Journal:  Immunology       Date:  2004-06       Impact factor: 7.397

2.  Expression of a dominant-negative Rho-kinase promotes neurite outgrowth in a microenvironment mimicking injured central nervous system.

Authors:  Ping Yang; Hui-zhong Wen; Jin-hai Zhang
Journal:  Acta Pharmacol Sin       Date:  2010-04-12       Impact factor: 6.150

3.  The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth.

Authors:  Jen-Zen Chuang; Ting-Yu Yeh; Flavia Bollati; Cecilia Conde; Federico Canavosio; Alfredo Caceres; Ching-Hwa Sung
Journal:  Dev Cell       Date:  2005-07       Impact factor: 12.270

4.  Rho GTPases regulate PTPmu-mediated nasal neurite outgrowth and temporal repulsion of retinal ganglion cell neurons.

Authors:  Denice L Major; Susann M Brady-Kalnay
Journal:  Mol Cell Neurosci       Date:  2007-01-17       Impact factor: 4.314

5.  NMDA receptor activation induces translocation and activation of Rac in mouse hippocampal area CA1.

Authors:  Maria V Tejada-Simon; Laura E Villasana; Faridis Serrano; Eric Klann
Journal:  Biochem Biophys Res Commun       Date:  2006-03-10       Impact factor: 3.575

Review 6.  Rewiring the injured CNS: lessons from the optic nerve.

Authors:  Larry Benowitz; Yuqin Yin
Journal:  Exp Neurol       Date:  2007-06-07       Impact factor: 5.330

7.  SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.

Authors:  Brant Hamel; Elizabeth Monaghan-Benson; Rafael J Rojas; Brenda R S Temple; Daniel J Marston; Keith Burridge; John Sondek
Journal:  J Biol Chem       Date:  2011-01-17       Impact factor: 5.157

8.  Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction.

Authors:  Yingchun Wang; Feng Yang; Yi Fu; Xiahe Huang; Wei Wang; Xinning Jiang; Marina A Gritsenko; Rui Zhao; Matthew E Monore; Olivier C Pertz; Samuel O Purvine; Daniel J Orton; Jon M Jacobs; David G Camp; Richard D Smith; Richard L Klemke
Journal:  J Biol Chem       Date:  2011-03-28       Impact factor: 5.157

9.  The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons.

Authors:  Junghwa Lim; Daniel A Ritt; Ming Zhou; Deborah K Morrison
Journal:  Curr Biol       Date:  2014-03-20       Impact factor: 10.834

10.  Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study.

Authors:  Petr Chlapek; Martina Redova; Karel Zitterbart; Marketa Hermanova; Jaroslav Sterba; Renata Veselska
Journal:  J Exp Clin Cancer Res       Date:  2010-05-11
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