Literature DB >> 11950561

Recombinant protein expression for therapeutic applications.

Dana C Andersen1, Lynne Krummen.   

Abstract

In recent years, the number of recombinant proteins used for therapeutic applications has increased dramatically. Many of these applications involve complex glycoproteins and antibodies with relatively high production needs. These demands have driven the development of a variety of improvements in protein expression technology, particularly involving mammalian and microbial culture systems.

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Year:  2002        PMID: 11950561     DOI: 10.1016/s0958-1669(02)00300-2

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  55 in total

1.  Expression of biologically active human interferon alpha 2b in the milk of transgenic mice.

Authors:  Hui Li; Qingyou Liu; Kuiqing Cui; Jinfeng Liu; Yanping Ren; Deshun Shi
Journal:  Transgenic Res       Date:  2012-06-03       Impact factor: 2.788

Review 2.  Generation and production of engineered antibodies.

Authors:  Sergey M Kipriyanov; Fabrice Le Gall
Journal:  Mol Biotechnol       Date:  2004-01       Impact factor: 2.695

3.  Fish eggs as bioreactors: the production of bioactive luteinizing hormone in transgenic trout embryos.

Authors:  Tetsuro Morita; Goro Yoshizaki; Makito Kobayashi; Shugo Watabe; Toshio Takeuchi
Journal:  Transgenic Res       Date:  2004-12       Impact factor: 2.788

4.  Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells.

Authors:  Peter Morin Nissom; Arleen Sanny; Yee Jiun Kok; Yeo Thong Hiang; Song Hui Chuah; Tan Kher Shing; Yih Yean Lee; Kathy Tin Kam Wong; Wei-Shou Hu; Miranda Yap Gek Sim; Robin Philp
Journal:  Mol Biotechnol       Date:  2006-10       Impact factor: 2.695

5.  Application of a reversible immortalization system for the generation of proliferation-controlled cell lines.

Authors:  Tobias May; Werner Lindenmaier; Dagmar Wirth; Peter P Mueller
Journal:  Cytotechnology       Date:  2005-11-30       Impact factor: 2.058

6.  Development of transfection and high-producer screening protocols for the CHOK1SV cell system.

Authors:  M Celina de la Cruz Edmonds; Melanie Tellers; Christine Chan; Peter Salmon; David K Robinson; Julia Markusen
Journal:  Mol Biotechnol       Date:  2006-10       Impact factor: 2.695

Review 7.  Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.

Authors:  Ricardo J Solá; Kai Griebenow
Journal:  BioDrugs       Date:  2010-02-01       Impact factor: 5.807

8.  The growth hormone-encoding gene isolated and characterized from Labeo rohita Hamilton is expressed in CHO cells under the control of constitutive promoters in 'autotransgene' constructs.

Authors:  R Rajesh; K C Majumdar
Journal:  Fish Physiol Biochem       Date:  2008-02-07       Impact factor: 2.794

Review 9.  Effects of glycosylation on the stability of protein pharmaceuticals.

Authors:  Ricardo J Solá; Kai Griebenow
Journal:  J Pharm Sci       Date:  2009-04       Impact factor: 3.534

10.  Efficient production of L-ribose with a recombinant Escherichia coli biocatalyst.

Authors:  Ryan D Woodyer; Nathan J Wymer; F Michael Racine; Shama N Khan; Badal C Saha
Journal:  Appl Environ Microbiol       Date:  2008-03-14       Impact factor: 4.792

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