| Literature DB >> 11942602 |
James N Weiss1, Peng-Sheng Chen, Zhilin Qu, Hrayr S Karagueuzian, Shin-Fong Lin, Alan Garfinkel.
Abstract
Combined experimental and theoretical work has shown that restitution properties of the cardiac action potential duration and conduction velocity contribute to breakup of reentrant wavefronts during cardiac fibrillation independent of preexisting electrophysiologic heterogeneities in the tissue. Developing therapies that favorably alter these cardiac electrical restitution properties are a promising new approach to preventing fibrillation.Entities:
Mesh:
Year: 2002 PMID: 11942602 DOI: 10.1046/j.1540-8167.2002.00292.x
Source DB: PubMed Journal: J Cardiovasc Electrophysiol ISSN: 1045-3873