| Literature DB >> 22460358 |
M Khaled Sabeh1, Hussein Kekhia, Calum A Macrae.
Abstract
Understanding the developmental basis of cardiac electrical activity has proven technically challenging, largely as a result of the inaccessible nature of the heart during cardiogenesis in many organisms. The emergence of the zebrafish as a model organism has availed the very earliest stages of heart formation to experimental exploration. The zebrafish also offers a robust platform for genetic and chemical screening. These tools have been exploited in screens for modifiers of cardiac electrophysiologic phenotypes and in screens for novel drugs.Entities:
Mesh:
Year: 2012 PMID: 22460358 DOI: 10.1007/s00246-012-0300-1
Source DB: PubMed Journal: Pediatr Cardiol ISSN: 0172-0643 Impact factor: 1.655