Literature DB >> 11932427

The carboxy terminus of simian virus 40 large T antigen is required to disrupt the yeast cell cycle.

Sheara W Fewell1, Dena M Markle, Jeffrey L Brodsky.   

Abstract

Wild-type and J domain mutant simian virus 40 large T antigens alter the cell cycle and bud morphology of Saccharomyces cerevisiae. In contrast, yeast cells expressing mutant T antigen lacking the carboxy-terminal 150 aa exhibit normal morphology, indicating that this region of T antigen is required for cell cycle disruption.

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Year:  2002        PMID： 11932427      PMCID： PMC155092          DOI： 10.1128/jvi.76.9.4621-4624.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  20 in total

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4.  Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene.

Authors:  J M Pipas; K W Peden; D Nathans
Journal:  Mol Cell Biol       Date:  1983-02       Impact factor: 4.272

5.  Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.

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6.  Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40.

Authors:  C S Sullivan; J D Tremblay; S W Fewell; J A Lewis; J L Brodsky; J M Pipas
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7.  Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain.

Authors:  Sheara W Fewell; James M Pipas; Jeffrey L Brodsky
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-19       Impact factor: 11.205

Review 8.  Common and unique features of T antigens encoded by the polyomavirus group.

Authors:  J M Pipas
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

9.  Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen.

Authors:  J Zhu; P W Rice; L Gorsch; M Abate; C N Cole
Journal:  J Virol       Date:  1992-05       Impact factor: 5.103

10.  Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

Authors:  M A Hoyt; L He; K K Loo; W S Saunders
Journal:  J Cell Biol       Date:  1992-07       Impact factor: 10.539
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