| Literature DB >> 11932007 |
Abstract
The inability of current technology to determine contiguous sequence for highly repetitive regions means that centromeres fall within multi-megabase gaps, analogous to black holes from which no information escapes. However, high-resolution mapping of a human X-centromere border reveals a remarkable structure, including a gradient of alpha-satellite divergence up to the edge of the youngest and most homogeneous repeats.Entities:
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Year: 2002 PMID: 11932007 DOI: 10.1016/s0168-9525(01)02622-1
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639