Literature DB >> 11927010

Multiplexed analysis of post-PCR fluorescence-labeled microsatellite alleles and statistical evaluation of their imbalance in brain tumors.

Koji Yoshimoto1, Toru Iwaki, Takanori Inamura, Masashi Fukui, Tomoko Tahira, Kenshi Hayashi.   

Abstract

Detection of the loss of chromosomal regions in cancerous tissues has diagnostic and prognostic relevance, and the development of a reliable and cost-effective technique for this is clinically important. Here we present an efficient technique for quantitative detection of microsatellite alleles, using a post-PCR fluorescence-labeling procedure and multiplexed analysis. We also present a new statistical method for the interpretation of the data that permits reliable and sensitive evaluation of the allelic status of sampled DNA. A high-resolution analysis of allelic imbalance on chromosomes 1p, 10 and 19q in 28 glioma samples of various types using this method revealed that allelic imbalances are more frequent than have been reported, suggesting the diagnostic value of this method in examining the genetic profiles of gliomas.

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Year:  2002        PMID： 11927010      PMCID： PMC5926965          DOI： 10.1111/j.1349-7006.2002.tb02170.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  25 in total

1.  Microsatellite genotyping of post-PCR fluorescently labeled markers.

Authors:  H Kondo; T Tahira; H Hayashi; K Oshima; K Hayashi
Journal:  Biotechniques       Date:  2000-10       Impact factor: 1.993

2.  Precise estimation of allele frequencies of single-nucleotide polymorphisms by a quantitative SSCP analysis of pooled DNA.

Authors:  T Sasaki; T Tahira; A Suzuki; K Higasa; Y Kukita; S Baba; K Hayashi
Journal:  Am J Hum Genet       Date:  2000-11-14       Impact factor: 11.025

3.  Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

Authors:  J S Smith; A Perry; T J Borell; H K Lee; J O'Fallon; S M Hosek; D Kimmel; A Yates; P C Burger; B W Scheithauer; R B Jenkins
Journal:  J Clin Oncol       Date:  2000-02       Impact factor: 44.544

4.  Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype.

Authors:  J S Smith; B Alderete; Y Minn; T J Borell; A Perry; G Mohapatra; S M Hosek; D Kimmel; J O'Fallon; A Yates; B G Feuerstein; P C Burger; B W Scheithauer; R B Jenkins
Journal:  Oncogene       Date:  1999-07-15       Impact factor: 9.867

Review 5.  Molecular pathogenesis of malignant gliomas.

Authors:  B K Rasheed; R N Wiltshire; S H Bigner; D D Bigner
Journal:  Curr Opin Oncol       Date:  1999-05       Impact factor: 3.645

6.  Chromosome 7q allelic losses in pancreatic carcinoma.

Authors:  A Achille; M O Biasi; G Zamboni; G Bogina; A R Magalini; P Pederzoli; M Perucho; A Scarpa
Journal:  Cancer Res       Date:  1996-08-15       Impact factor: 12.701

7.  Low frequency of replication errors in primary nervous system tumours.

Authors:  M J Sobrido; C R Pereira; F Barros; J Forteza; A Carracedo; M Lema
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-09       Impact factor: 10.154

8.  Deletion mapping of chromosome 19 in human gliomas.

Authors:  A von Deimling; J Nagel; B Bender; D Lenartz; J Schramm; D N Louis; O D Wiestler
Journal:  Int J Cancer       Date:  1994-06-01       Impact factor: 7.396

9.  Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.

Authors:  A von Deimling; B Bender; R Jahnke; A Waha; J Kraus; S Albrecht; R Wellenreuther; F Fassbender; J Nagel; A G Menon
Journal:  Cancer Res       Date:  1994-03-15       Impact factor: 12.701

10.  Deletion mapping of chromosome 10 in human glioma.

Authors:  Y Sonoda; Y Murakami; T Tominaga; T Kayama; T Yoshimoto; T Sekiya
Journal:  Jpn J Cancer Res       Date:  1996-04
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  6 in total

1.  An astroblastoma case associated with loss of heterozygosity on chromosome 9p.

Authors:  Nobuhiro Hata; Tadahisa Shono; Koji Yoshimoto; Masahiro Mizoguchi; Tadao Kawamura; Shinji Nagata; Kenichi Matsumoto; Kenshi Hayashi; Toru Iwaki; Tomio Sasaki
Journal:  J Neurooncol       Date:  2006-04-25       Impact factor: 4.130

2.  Genetic analysis of a case of glioblastoma with oligodendroglial component arising during the progression of diffuse astrocytoma.

Authors:  Nobuhiro Hata; Satoshi O Suzuki; Hideki Murata; Ryusuke Hatae; Yojiro Akagi; Yuhei Sangatsuda; Toshiyuki Amano; Koji Yoshimoto; Tomoko Tahira; Masahiro Mizoguchi
Journal:  Pathol Oncol Res       Date:  2014-10-30       Impact factor: 3.201

Review 3.  Diagnostic test accuracy and cost-effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma.

Authors:  Alexandra McAleenan; Hayley E Jones; Ashleigh Kernohan; Tomos Robinson; Lena Schmidt; Sarah Dawson; Claire Kelly; Emmelyn Spencer Leal; Claire L Faulkner; Abigail Palmer; Christopher Wragg; Sarah Jefferies; Sebastian Brandner; Luke Vale; Julian Pt Higgins; Kathreena M Kurian
Journal:  Cochrane Database Syst Rev       Date:  2022-03-02

4.  Prevalence of copy-number neutral LOH in glioblastomas revealed by genomewide analysis of laser-microdissected tissues.

Authors:  Daisuke Kuga; Masahiro Mizoguchi; Yanlei Guan; Nobuhiro Hata; Koji Yoshimoto; Tadahisa Shono; Satoshi O Suzuki; Yoji Kukita; Tomoko Tahira; Shinji Nagata; Tomio Sasaki; Kenshi Hayashi
Journal:  Neuro Oncol       Date:  2008-08-12       Impact factor: 12.300

5.  TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.

Authors:  Hideyuki Arita; Yuko Matsushita; Ryunosuke Machida; Kai Yamasaki; Nobuhiro Hata; Makoto Ohno; Shigeru Yamaguchi; Takashi Sasayama; Shota Tanaka; Fumi Higuchi; Toshihiko Iuchi; Kuniaki Saito; Masayuki Kanamori; Ken-Ichiro Matsuda; Yohei Miyake; Kaoru Tamura; Sho Tamai; Taishi Nakamura; Takehiro Uda; Yoshiko Okita; Junya Fukai; Daisuke Sakamoto; Yasuhiko Hattori; Eriel Sandika Pareira; Ryusuke Hatae; Yukitomo Ishi; Yasuji Miyakita; Kazuhiro Tanaka; Shunsaku Takayanagi; Ryohei Otani; Tsukasa Sakaida; Keiichi Kobayashi; Ryuta Saito; Kazuhiko Kurozumi; Tomoko Shofuda; Masahiro Nonaka; Hiroyoshi Suzuki; Makoto Shibuya; Takashi Komori; Hikaru Sasaki; Masahiro Mizoguchi; Haruhiko Kishima; Mitsutoshi Nakada; Yukihiko Sonoda; Teiji Tominaga; Motoo Nagane; Ryo Nishikawa; Yonehiro Kanemura; Aya Kuchiba; Yoshitaka Narita; Koichi Ichimura
Journal:  Acta Neuropathol Commun       Date:  2020-11-23       Impact factor: 7.578

6.  A tailored next-generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas.

Authors:  Nayuta Higa; Toshiaki Akahane; Seiya Yokoyama; Hajime Yonezawa; Hiroyuki Uchida; Tomoko Takajo; Mari Kirishima; Taiji Hamada; Kei Matsuo; Shingo Fujio; Tomoko Hanada; Hiroshi Hosoyama; Masanori Yonenaga; Akihisa Sakamoto; Tsubasa Hiraki; Akihide Tanimoto; Koji Yoshimoto
Journal:  Cancer Sci       Date:  2020-09-06       Impact factor: 6.716
  6 in total

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