| Literature DB >> 11911884 |
Harald Stenmark1, Rein Aasland, Paul C Driscoll.
Abstract
The FYVE zinc finger domain is conserved from yeast (five proteins) to man (27 proteins). It functions in the membrane recruitment of cytosolic proteins by binding to phosphatidylinositol 3-phosphate (PI3P), which is found mainly on endosomes. Here we review recent work that sheds light on the targeting of FYVE finger proteins to PI3P-containing membranes, and how these proteins serve to regulate multiple cellular functions.Entities:
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Year: 2002 PMID: 11911884 DOI: 10.1016/s0014-5793(01)03308-7
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124