Literature DB >> 1190779

Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice.

G M Holder, H Yagi, D M Jerina, W Levin, A Y Lu, A H Conney.   

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Year:  1975        PMID： 1190779     DOI： 10.1016/0003-9861(75)90151-4

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


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  12 in total

1.  In vitro metabolism and in vivo binding of benzo(a)pyrene in the California killifish (Fundulus parvipinnis) and speckled sanddab (Citharicthys stigmaeous).

Authors:  E von Hofe; H W Puffer
Journal:  Arch Environ Contam Toxicol       Date:  1986-05       Impact factor: 2.804

2.  Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene.

Authors:  P Bentley; F Oesch; H Glatt
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

3.  Birth defects and aplastic anemia: differences in polycyclic hydrocarbon toxicity associated with the Ah locus.

Authors:  D W Nebert; R C Levitt; N M Jensen; G H Lambert; J S Felton
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

4.  Enzymic control of irreversible binding of metabolically activated benzo(a)pyrene in perfused rat liver by monooxygenase activity.

Authors:  G F Kahl; E Klaus; H G Jonen; R Kahl
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

5.  Effects of polychlorinated terphenyls and paraffins on rat liver microsomal cytochrome P-450 and in vitro metabolic activities.

Authors:  O G Nilsen; R Toftgård
Journal:  Arch Toxicol       Date:  1981-03       Impact factor: 5.153

6.  Specificity of chemiluminescence in the metabolism of benzo[a]pyrene to its carcinogenic diol epoxide.

Authors:  J P Hamman; H H Seliger; G H Posner
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

7.  Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.

Authors:  D R Thakker; H Yagi; A Y Lu; W Levin; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

8.  Effects of chlorinated paraffins on rat liver microsomal activities and morphology. Importance of the length and the degree of chlorination of the carbon chain.

Authors:  O G Nilsen; R Toftgård; H Glaumann
Journal:  Arch Toxicol       Date:  1981-11       Impact factor: 5.153

9.  Induction of ouabain-resistant mutation and sister chromatid exchanges in Chinese hamster cells with chemical carcinogens mediated by human pulmonary macrophages.

Authors:  I C Hsu; C C Harris; M Yamaguchi; B F Trump; P W Schafer
Journal:  J Clin Invest       Date:  1979-11       Impact factor: 14.808

10.  Vitamin K as a regulator of benzo(a)pyrene metabolism, mutagenesis, and carcinogenesis. Studies with rat microsomes and tumorigenesis in mice.

Authors:  L G Israels; G A Walls; D J Ollmann; E Friesen; E D Israels
Journal:  J Clin Invest       Date:  1983-05       Impact factor: 14.808
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