Literature DB >> 11903366

An evaluation of the best head position for instillation of steroid nose drops.

R Kayarkar1, N J Clifton, T J Woolford.   

Abstract

Steroid nose drops are used frequently to treat rhinosinusitis and nasal polyposis. The middle meatal area is of key importance in the pathophysiology of these conditions. This study assesses which of three head positions commonly used to instil nose drops resulted in the highest coverage of this area. Discomfort levels were also studied using a visual analogue scale for each position. Five volunteers were studied in: (i) head back (HB); (ii) head forward and down (HFD); and (iii) lying head back (LHB) positions. Betamethasone nose drops, dyed with fluorescein, were instilled into each nostril and the distribution was studied endoscopically. The middle meatus area distribution was highest in the LHB position (55.51%), followed by HFD (31.55%) and HB (6.87%) positions. Comparison of distribution between HB and LHB (P = 0.002) and between HB and HFD (P = 0.045) was statistically significant. The HFD position was most uncomfortable (mean discomfort score 8.8) whereas the HB (2.4) and LHB (2.6) were similar. The LHB would, therefore, appear to be the most suitable position for instillation of steroid nose drops.

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Year:  2002        PMID: 11903366     DOI: 10.1046/j.1365-2273.2002.00515.x

Source DB:  PubMed          Journal:  Clin Otolaryngol Allied Sci        ISSN: 0307-7772


  11 in total

1.  Influence of anatomy and head position on intranasal drug deposition.

Authors:  Paul Merkus; Fenna A Ebbens; Barbara Muller; Wytske J Fokkens
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-06-29       Impact factor: 2.503

2.  The administration of nasal drops in the "Kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects.

Authors:  Eri Mori; Christos Merkonidis; Mandy Cuevas; Volker Gudziol; Yoshinori Matsuwaki; Thomas Hummel
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-07-04       Impact factor: 2.503

3.  Olfaction in chronic rhinosinusitis: comparing two different endonasal steroid application methods.

Authors:  Sophia C Poletti; Islam Batashev; Jens Reden; Thomas Hummel
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-10-11       Impact factor: 2.503

Review 4.  Update on Intranasal Medications in Rhinosinusitis.

Authors:  Kornkiat Snidvongs; Sanguansak Thanaviratananich
Journal:  Curr Allergy Asthma Rep       Date:  2017-07       Impact factor: 4.806

Review 5.  Pathogenesis and management of nasal polyposis in cystic fibrosis.

Authors:  Jochen G Mainz; Assen Koitschev
Journal:  Curr Allergy Asthma Rep       Date:  2012-04       Impact factor: 4.806

6.  Topical Drug Delivery for Chronic Rhinosinusitis.

Authors:  Jonathan Liang; Andrew P Lane
Journal:  Curr Otorhinolaryngol Rep       Date:  2012-12-27

7.  Bioabsorbable steroid-releasing implants in the frontal sinus ostia: a pooled analysis.

Authors:  Ameet Singh; Amber U Luong; Karen J Fong; Randall A Ow; Joseph K Han; Roland Gerencer; J Pablo Stolovitzky; James W Stambaugh; Aarthi Raman
Journal:  Int Forum Allergy Rhinol       Date:  2018-11-15       Impact factor: 3.858

Review 8.  Novel drug-delivery systems for patients with chronic rhinosinusitis.

Authors:  Silviu Albu
Journal:  Drug Des Devel Ther       Date:  2012-05-31       Impact factor: 4.162

9.  A review of nasal polyposis.

Authors:  Jonathan Ray Newton; Kim Wong Ah-See
Journal:  Ther Clin Risk Manag       Date:  2008-04       Impact factor: 2.423

10.  BSACI guidelines for the management of allergic and non-allergic rhinitis.

Authors:  G K Scadding; S R Durham; R Mirakian; N S Jones; S C Leech; S Farooque; D Ryan; S M Walker; A T Clark; T A Dixon; S R A Jolles; N Siddique; P Cullinan; P H Howarth; S M Nasser
Journal:  Clin Exp Allergy       Date:  2008-01       Impact factor: 5.018

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