Literature DB >> 11902573

The promise of retinoids to fight against cancer.

L Altucci1, H Gronemeyer.   

Abstract

Retinoids have a reputation for being both detrimental and beneficial: they are teratogens, but they also have tumour-suppressive capacity. Cell biology and genetics have significantly improved our understanding of the mechanisms that underlie the anti-proliferative action of retinoids. Recent elucidation of the pathways that are activated by retinoids will help us to exploit the beneficial aspects of this powerful class of compounds for cancer therapy and prevention.

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Year:  2001        PMID: 11902573     DOI: 10.1038/35106036

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  191 in total

1.  Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.

Authors:  Angela Maria Di Francesco; Paolo Ubezio; Anna Rita Torella; Daniela Meco; Filomena Pierri; Giuseppe Barone; Gabriella Cusano; Claudio Pisano; Maurizio D'Incalci; Riccardo Riccardi
Journal:  Invest New Drugs       Date:  2011-06-03       Impact factor: 3.850

2.  Intake of fruit, vegetables, and carotenoids in relation to risk of uterine leiomyomata.

Authors:  Lauren A Wise; Rose G Radin; Julie R Palmer; Shiriki K Kumanyika; Deborah A Boggs; Lynn Rosenberg
Journal:  Am J Clin Nutr       Date:  2011-11-09       Impact factor: 7.045

3.  Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.

Authors:  Wendell S Fortson; Shubhalaxmi Kayarthodi; Yasuo Fujimura; Huali Xu; Roland Matthews; William E Grizzle; Veena N Rao; Ganapathy K Bhat; E Shyam P Reddy
Journal:  Int J Oncol       Date:  2011-04-21       Impact factor: 5.650

4.  Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.

Authors:  Tino Schenk; Weihsu Claire Chen; Stefanie Göllner; Louise Howell; Liqing Jin; Katja Hebestreit; Hans-Ulrich Klein; Andreea C Popescu; Alan Burnett; Ken Mills; Robert A Casero; Laurence Marton; Patrick Woster; Mark D Minden; Martin Dugas; Jean C Y Wang; John E Dick; Carsten Müller-Tidow; Kevin Petrie; Arthur Zelent
Journal:  Nat Med       Date:  2012-03-11       Impact factor: 53.440

5.  Retinoic acid exerts dual regulatory actions on the expression and nuclear localization of interferon regulatory factor-1.

Authors:  Xin M Luo; A Catharine Ross
Journal:  Exp Biol Med (Maywood)       Date:  2006-05

6.  Impairment of p53 acetylation, stability and function by an oncogenic transcription factor.

Authors:  Alessandra Insinga; Silvia Monestiroli; Simona Ronzoni; Roberta Carbone; Mark Pearson; Giancarlo Pruneri; Giuseppe Viale; Ettore Appella; PierGiuseppe Pelicci; Saverio Minucci
Journal:  EMBO J       Date:  2004-02-19       Impact factor: 11.598

7.  Synergistic growth inhibition in HL-60 cells by the combination of acyclic retinoid and vitamin K2.

Authors:  Junichi Kitagawa; Takeshi Hara; Hisashi Tsurumi; Soranobu Ninomiya; Kengo Ogawa; Seiji Adachi; Nobuhiro Kanemura; Senji Kasahara; Masahito Shimizu; Hisataka Moriwaki
Journal:  J Cancer Res Clin Oncol       Date:  2010-07-31       Impact factor: 4.553

8.  Expression and functional analysis of two lycopene β-cyclases from citrus fruits.

Authors:  Lancui Zhang; Gang Ma; Yuki Shirai; Masaya Kato; Kazuki Yamawaki; Yoshinori Ikoma; Hikaru Matsumoto
Journal:  Planta       Date:  2012-06-24       Impact factor: 4.116

9.  A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency.

Authors:  Carl R Walkley; Gemma Haines Olsen; Sebastian Dworkin; Stewart A Fabb; Jeremy Swann; Grant A McArthur; Susan V Westmoreland; Pierre Chambon; David T Scadden; Louise E Purton
Journal:  Cell       Date:  2007-06-15       Impact factor: 41.582

10.  Targeting sarcoma tumor-initiating cells through differentiation therapy.

Authors:  Dan Han; Veronica Rodriguez-Bravo; Elizabeth Charytonowicz; Elizabeth Demicco; Josep Domingo-Domenech; Robert G Maki; Carlos Cordon-Cardo
Journal:  Stem Cell Res       Date:  2017-04-13       Impact factor: 2.020

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