| Literature DB >> 11902440 |
Alexey Teplyakov1, Caroline Leriche, Galya Obmolova, Bernard Badet, Marie-Ange Badet-Denisot.
Abstract
This review summarizes the state of knowledge on D-glucosamine-6P synthesis catalyzed by glucosamine-6P synthase. The mechanisms of L-glutamine hydrolysis, ammonia transfer and fructose-6P conversion into D-glucosamine-6P are analyzed with the E. coli enzyme in light of recent X-ray structures. With 92 references this paper covers the literature up to June 2001 and emphasizes the potential implication of the mammalian glucosamine-6P synthase in type 2 diabetes.Entities:
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Year: 2002 PMID: 11902440 DOI: 10.1039/b103713g
Source DB: PubMed Journal: Nat Prod Rep ISSN: 0265-0568 Impact factor: 13.423