Literature DB >> 1190201

Evaluation of endoscopic examination of colon tumors in rats.

T Narisawa, C Q Wong, J H Weisburger.   

Abstract

This study is an evaluation of the use of endoscopic examination to detect MNNG-induced large-bowel tumors in rats. The smallest human fiberbronchoscope was used as a colonoscope for the rats and the full length of the distal large bowel was visualized. The correct diagnosis rate in all rats with and without large-bowel tumors was 94%. Of rats with colon tumors, 85% were correctly diagnosed endoscopically. Even tumors 1 or 2 mm in diameter were detected. The examination was easy and reliable. This procedure may be an adjunct in experimental work with this and other animal models of colon cancer.

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Year:  1975        PMID: 1190201     DOI: 10.1007/bf01070878

Source DB:  PubMed          Journal:  Am J Dig Dis        ISSN: 0002-9211


  13 in total

Review 1.  Chemical carcinogens and their mode of action in colonic neoplasia.

Authors:  J H Weisburger
Journal:  Dis Colon Rectum       Date:  1973 Nov-Dec       Impact factor: 4.585

2.  Serial endoscopic evaluation of experimental gastric cancer.

Authors:  C Sugawa; C E Lucas; A J Walt
Journal:  Gastrointest Endosc       Date:  1974-02       Impact factor: 9.427

3.  Induction of adenocarcinomas of the colon in mice by weekly injections of 1,2-dimethylhydrazine.

Authors:  N Thurnherr; E E Deschner; E H Stonehill; M Lipkin
Journal:  Cancer Res       Date:  1973-05       Impact factor: 12.701

4.  Induction of carcinomas of the colon and rectum in rats by intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  B T So; N E Magadia; E L Wynder
Journal:  J Natl Cancer Inst       Date:  1973-04       Impact factor: 13.506

5.  Dietary hypotheses and diet-related research in the etiology of colon cancer.

Authors:  J W Berg; M A Howell; S J Silverman
Journal:  Health Serv Rep       Date:  1973-12

6.  Carcinoma of the colon and rectum of rats by rectal infusion of N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  T Narisawa; T Sato; M Hayakawa; A Sakuma; H Nakano
Journal:  Gan       Date:  1971-06

7.  [Selective production of intestinal cancer in rats by 1,2-dimethylhydrazine].

Authors:  H Druckrey; R Preussmann; F Matzkies; S Ivankovic
Journal:  Naturwissenschaften       Date:  1967-06

8.  Tumour production in glandular stomach of rat by N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  T Sugimura; S Fujimura
Journal:  Nature       Date:  1967-12-02       Impact factor: 49.962

9.  Induction of carcinoma of the large intestine in guinea pigs by intratectal instillation of N-methyl-N-nitrosourea.

Authors:  T Narisawa; C Q Wong; J H Weisburger
Journal:  J Natl Cancer Inst       Date:  1975-03       Impact factor: 13.506

10.  Colon cancer induction in mice by intrarectal instillation of N-methylnitosorurea (38498).

Authors:  T Narisawa; J H Weisburger
Journal:  Proc Soc Exp Biol Med       Date:  1975-01
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  10 in total

1.  Development of a total colonoscopy rat model with endoscopic submucosal injection of the cecal wall.

Authors:  C Haughn; M Uchal; Y Raftopoulos; S Rossi; T Santucci; M Torpey; A Pollice; Y Yavuz; Y Yavus; R Marvik; R Bergamaschi
Journal:  Surg Endosc       Date:  2005-12-06       Impact factor: 4.584

2.  Activity of two platinum-linked phosphonic acids against autochthonous rat colorectal cancer as well as in two human colon-cancer cell lines.

Authors:  A Galeano; M R Berger; B K Keppler
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Antineoplastic activity of three ruthenium derivatives against chemically induced colorectal carcinoma in rats.

Authors:  M H Seelig; M R Berger; B K Keppler
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

4.  [Effect of local moderate hyperthermia in combination with N-nitroso-1,3-bis-(2-chloroethyl)urea (BCNU) and 5-fluoro-(tetrahydro-2-furyl)uracil (ftorafur) on induced autochthonous colonic cancers in the rat. 3: Polychemotherapy in combination with hyperthermia].

Authors:  E Biwer; M Lorenz; M Habs; D Schmähl
Journal:  Langenbecks Arch Chir       Date:  1984

5.  Colonoscopy in rats: An endoscopic, histological and tomographic study.

Authors:  Ramon Bartolí; Jaume Boix; Gemma Odena; Napoleón D De la Ossa; Vicente Moreno de Vega; Vicente Lorenzo-Zúñiga
Journal:  World J Gastrointest Endosc       Date:  2013-05-16

6.  Combination chemotherapy with 5-fluorouracil (5FU) and 1,3-bis(2-chloro-ethyl)-1-nitrosourea (BCNU) prolongs survival of rats with dimethylhydrazine-induced colon cancer.

Authors:  M Danzi; M R Lewin; J P Cruse; C G Clark
Journal:  Gut       Date:  1983-11       Impact factor: 23.059

7.  Chemotherapeutic studies on N-nitrosoacetoxymethyl-methylamine-and 1,2-dimethylhydrazine-induced colonic tumors in rats: monotherapy with 5-fluorouracil, ftorafur, CGP 6809, and CGP 15'720A.

Authors:  I Wagner; M Habs; D Schmähl; H Amberger; U Bachmann
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

8.  Comparative antitumor activity of ruthenium derivatives with 5'-deoxy-5-fluorouridine in chemically induced colorectal tumors in SD rats.

Authors:  F T Garzon; M R Berger; B K Keppler; D Schmähl
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

9.  Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.

Authors:  T Narisawa; M Sato; M Tani; T Takahashi
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

10.  Endoscopic submucosal injection of adipose-derived mesenchymal stem cells ameliorates TNBS-induced colitis in rats and prevents stenosis.

Authors:  Eduardo Martín Arranz; María Dolores Martín Arranz; Tomás Robredo; Pablo Mancheño-Corvo; Ramón Menta; Francisco Javier Alves; Jose Manuel Suárez de Parga; Pedro Mora Sanz; Olga de la Rosa; Dirk Büscher; Eleuterio Lombardo; Fernando de Miguel
Journal:  Stem Cell Res Ther       Date:  2018-04-10       Impact factor: 6.832

  10 in total

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