Literature DB >> 11899183

Conversion to off-pump coronary bypass without increased morbidity or change in practice.

Ani C Anyanwu1, Sharif Al-Ruzzeh, Shane J George, Rikin Patel, Magdi H Yacoub, Mohamed Amrani.   

Abstract

BACKGROUND: This article examines the feasibility of complete conversion from conventional coronary artery operation to routine off-pump coronary bypass operation.
METHODS: Data on our first 285 off-pump procedures using the Octopus system (Medtronic Inc, Minneapolis, MN) represent our learning curve. This is a complete experience in coronary bypass surgery over 16 months.
RESULTS: The cohort was nonselected. All patients had at least two-vessel disease. Eight hundred seven grafts were performed (mean, 2.8 per patient) of which 647 grafts (84%) were arterial (mean, 2.3 per patient). One hundred seventy nine patients (63%) underwent total arterial revascularization. Eight patients required cardiopulmonary bypass; all other operations were completed off-pump. Complications were: mortality, 3 patients (1.5%); renal failure, 24 patients (8%); stroke, 2 patients (< 1%); and atrial fibrillation, 60 patients (21%). The morbidity data and frequency of arterial grafting did not differ from that of 355 patients who underwent coronary bypass operations in a preceding 18-month period.
CONCLUSIONS: Complete shift from routine use of cardiopulmonary bypass to nonselective off-pump coronary bypass operation is possible with a low conversion rate and without an apparent increase in morbidity or change in technique. Whereas short-term safety and efficacy seem certain, studies of long-term outcome are necessary before the eventual role of off-pump coronary bypass in myocardial revascularization can be defined.

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Year:  2002        PMID: 11899183     DOI: 10.1016/s0003-4975(01)03415-4

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  7 in total

1.  Effect of myocardial reperfusion on the release of nitric oxide after regional ischemia: an experimental model of beating-heart surgery.

Authors:  Koki Nakamura; Sharif Al-Ruzzeh; Caroline Gray; Magdi Yacoub; Mohamed Amrani
Journal:  Tex Heart Inst J       Date:  2006

Review 2.  Coronary artery bypass.

Authors:  Ian Weir
Journal:  Ann R Coll Surg Engl       Date:  2006-03       Impact factor: 1.891

Review 3.  Two decades of off-pump coronary artery bypass surgery: Harefield experience.

Authors:  Shahzad G Raja
Journal:  J Thorac Dis       Date:  2016-11       Impact factor: 2.895

4.  Effect of off-pump coronary artery bypass surgery on clinical, angiographic, neurocognitive, and quality of life outcomes: randomised controlled trial.

Authors:  Sharif Al-Ruzzeh; Shane George; Mahmoud Bustami; Jo Wray; Charles Ilsley; Thanos Athanasiou; Mohamed Amrani
Journal:  BMJ       Date:  2006-06-01

5.  Full-sternotomy off-pump versus on-pump coronary artery bypass procedures: in-hospital outcomes and complications during one year in a single center.

Authors:  Tomaso Bottio; Giulio Rizzoli; Luca Caprili; Georgios Nesseris; Gaetano Thiene; Gino Gerosa
Journal:  Tex Heart Inst J       Date:  2003

6.  Effects of preoperative magnesium therapy on arrhythmias and myocardial ischemia during off-pump coronary surgery.

Authors:  Yavuz Beşoğul; Hüseyin Gemalmaz; Recep Aslan
Journal:  Ann Thorac Med       Date:  2009-07       Impact factor: 2.219

7.  Comparison of off-pump and on-pump coronary artery bypass grafting in midterm results.

Authors:  Michiko Ishida; Junjiro Kobayashi; Osamu Tagusari; Ko Bando; Kazuo Niwaya; Hiroyuki Nakajima; Satsuki Fukushima; Soichiro Kitamura
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2004-05
  7 in total

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