Literature DB >> 11896237

Solution of a 20-variable 3-SAT problem on a DNA computer.

Ravinderjit S Braich1, Nickolas Chelyapov, Cliff Johnson, Paul W K Rothemund, Leonard Adleman.   

Abstract

A 20-variable instance of the NP-complete three-satisfiability (3-SAT) problem was solved on a simple DNA computer. The unique answer was found after an exhaustive search of more than 1 million (2(20)) possibilities. This computational problem may be the largest yet solved by nonelectronic means. Problems of this size appear to be beyond the normal range of unaided human computation.

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Year:  2002        PMID： 11896237     DOI： 10.1126/science.1069528

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  42 in total

1.  DNA molecule provides a computing machine with both data and fuel.

Authors:  Yaakov Benenson; Rivka Adar; Tamar Paz-Elizur; Zvi Livneh; Ehud Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-24       Impact factor: 11.205

2.  Shaping up nucleic acid computation.

Authors:  Xi Chen; Andrew D Ellington
Journal:  Curr Opin Biotechnol       Date:  2010-06-09       Impact factor: 9.740

3.  RNAsoft: A suite of RNA secondary structure prediction and design software tools.

Authors:  Mirela Andronescu; Rosalía Aguirre-Hernández; Anne Condon; Holger H Hoos
Journal:  Nucleic Acids Res       Date:  2003-07-01       Impact factor: 16.971

4.  Demonstration of a universal surface DNA computer.

Authors:  Xingping Su; Lloyd M Smith
Journal:  Nucleic Acids Res       Date:  2004-06-04       Impact factor: 16.971

5.  DNA computing using single-molecule hybridization detection.

Authors:  Kristiane A Schmidt; Christiaan V Henkel; Grzegorz Rozenberg; Herman P Spaink
Journal:  Nucleic Acids Res       Date:  2004-09-23       Impact factor: 16.971

6.  Paradigms for computational nucleic acid design.

Authors:  Robert M Dirks; Milo Lin; Erik Winfree; Niles A Pierce
Journal:  Nucleic Acids Res       Date:  2004-02-27       Impact factor: 16.971

7.  Training a molecular automaton to play a game.

Authors:  Renjun Pei; Elizabeth Matamoros; Manhong Liu; Darko Stefanovic; Milan N Stojanovic
Journal:  Nat Nanotechnol       Date:  2010-10-24       Impact factor: 39.213

8.  Molecular computing by PNA:PNA duplex formation.

Authors:  Filbert Totsingan; Rosangela Marchelli; Roberto Corradini
Journal:  Artif DNA PNA XNA       Date:  2011-01

9.  Multiplying with DNA.

Authors:  Gang Wu; Nadrian C Seeman
Journal:  Nat Comput       Date:  2006-11       Impact factor: 1.690

10.  Parallel computation with molecular-motor-propelled agents in nanofabricated networks.

Authors:  Dan V Nicolau; Mercy Lard; Till Korten; Falco C M J M van Delft; Malin Persson; Elina Bengtsson; Alf Månsson; Stefan Diez; Heiner Linke; Dan V Nicolau
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-22       Impact factor: 11.205
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