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Literature DB >> 11895630

Oral tolerance of food.

Abstract

The gut-associated lymphoid tissue is the specialized arm of the immune system responsible for distinguishing innocuous dietary nutrients, self-proteins, and gut flora from pathogens. Oral tolerance is the active immunologic response to innocuous ingested antigens that leads to a systemic tolerance for that antigen. This process holds great promise for dealing with the host of immune disorders that occur when an inappropriate and destructive immune response is induced. Improved therapies for disorders such as autoimmune disease and allergy are being actively investigated.

Entities: Disease

Mesh：

Year: 2002 PMID： 11895630 DOI： 10.1007/s11882-002-0043-9

Source DB: PubMed Journal: Curr Allergy Asthma Rep ISSN： 1529-7322 Impact factor: 4.806

27 in total

1. Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells.

Authors: H N Shi; M J Grusby; C Nagler-Anderson
Journal: J Immunol Date: 1999-05-01 Impact factor: 5.422

2. Oral tolerance, an active immunologic process mediated by multiple mechanisms.

Authors: H L Weiner
Journal: J Clin Invest Date: 2000-10 Impact factor: 14.808

Review 3. Oral tolerance.

Authors: K M Smith; A D Eaton; L M Finlayson; P Garside
Journal: Am J Respir Crit Care Med Date: 2000-10 Impact factor: 21.405

4. Induction of oral tolerance in TGF-beta 1 null mice.

Authors: K S Barone; D D Tolarova; I Ormsby; T Doetschman; J G Michael
Journal: J Immunol Date: 1998-07-01 Impact factor: 5.422

Review 5. Oral tolerance in disease.

Authors: P Garside; A M Mowat; A Khoruts
Journal: Gut Date: 1999-01 Impact factor: 23.059

6. Oral tolerance revisited: prior oral tolerization abrogates cholera toxin-induced mucosal IgA responses.

Authors: H Kato; K Fujihashi; R Kato; Y Yuki; J R McGhee
Journal: J Immunol Date: 2001-03-01 Impact factor: 5.422

7. Oral administration of hapten inhibits in vivo induction of specific cytotoxic CD8+ T cells mediating tissue inflammation: a role for regulatory CD4+ T cells.

Authors: C Desvignes; N Etchart; J Kehren; I Akiba; J F Nicolas; D Kaiserlian
Journal: J Immunol Date: 2000-03-01 Impact factor: 5.422

8. Induction of immune tolerance to human type I collagen in patients with systemic sclerosis by oral administration of bovine type I collagen.

Authors: K M McKown; L D Carbone; J Bustillo; J M Seyer; A H Kang; A E Postlethwaite
Journal: Arthritis Rheum Date: 2000-05