Literature DB >> 11893497

RNAi: nature abhors a double-strand.

György Hutvágner1, Phillip D Zamore.   

Abstract

In organisms as diverse as nematodes, trypanosomes, plants, and fungi, double-stranded RNA triggers the destruction of homologous mRNAs, a phenomenon known as RNA interference. RNA interference begins with the transformation of the double-stranded RNA into small RNAs that then guide a protein nuclease to destroy their mRNA targets.

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Year:  2002        PMID: 11893497     DOI: 10.1016/s0959-437x(02)00290-3

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  145 in total

1.  RNA-directed DNA methylation in Arabidopsis.

Authors:  Werner Aufsatz; M Florian Mette; Johannes van der Winden; Antonius J M Matzke; Marjori Matzke
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-08       Impact factor: 11.205

2.  Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing.

Authors:  Alicia M Celotto; Brenton R Graveley
Journal:  RNA       Date:  2002-06       Impact factor: 4.942

3.  RNAi functions in cultured mammalian neurons.

Authors:  Anna M Krichevsky; Kenneth S Kosik
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-21       Impact factor: 11.205

4.  RNA target sequences promote spreading of RNA silencing.

Authors:  Helena Van Houdt; Annick Bleys; Anna Depicker
Journal:  Plant Physiol       Date:  2003-01       Impact factor: 8.340

5.  Sequence requirements for micro RNA processing and function in human cells.

Authors:  Yan Zeng; Bryan R Cullen
Journal:  RNA       Date:  2003-01       Impact factor: 4.942

6.  Antisense transcripts with FANTOM2 clone set and their implications for gene regulation.

Authors:  Hidenori Kiyosawa; Itaru Yamanaka; Naoki Osato; Shinji Kondo; Yoshihide Hayashizaki
Journal:  Genome Res       Date:  2003-06       Impact factor: 9.043

7.  An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei.

Authors:  Appolinaire Djikeng; Huafang Shi; Christian Tschudi; Shuiyuan Shen; Elisabetta Ullu
Journal:  RNA       Date:  2003-07       Impact factor: 4.942

8.  Lentivirus-delivered stable gene silencing by RNAi in primary cells.

Authors:  Sheila A Stewart; Derek M Dykxhoorn; Deborah Palliser; Hana Mizuno; Evan Y Yu; Dong Sung An; David M Sabatini; Irvin S Y Chen; William C Hahn; Phillip A Sharp; Robert A Weinberg; Carl D Novina
Journal:  RNA       Date:  2003-04       Impact factor: 4.942

9.  Drosha as an interferon-independent antiviral factor.

Authors:  Jillian S Shapiro; Sonja Schmid; Lauren C Aguado; Leah R Sabin; Ari Yasunaga; Jaehee V Shim; David Sachs; Sara Cherry; Benjamin R tenOever
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-28       Impact factor: 11.205

10.  Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells.

Authors:  Elizabeth A Lipscomb; Aisling S Dugan; Isaac Rabinovitz; Arthur M Mercurio
Journal:  Clin Exp Metastasis       Date:  2003       Impact factor: 5.150

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