| Literature DB >> 11893497 |
György Hutvágner1, Phillip D Zamore.
Abstract
In organisms as diverse as nematodes, trypanosomes, plants, and fungi, double-stranded RNA triggers the destruction of homologous mRNAs, a phenomenon known as RNA interference. RNA interference begins with the transformation of the double-stranded RNA into small RNAs that then guide a protein nuclease to destroy their mRNA targets.Mesh:
Substances:
Year: 2002 PMID: 11893497 DOI: 10.1016/s0959-437x(02)00290-3
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578