| Literature DB >> 11893328 |
Abstract
When bacterial lineages make the transition from free-living or facultatively parasitic life cycles to permanent associations with hosts, they undergo a major loss of genes and DNA. Complete genome sequences are providing an understanding of how extreme genome reduction affects evolutionary directions and metabolic capabilities of obligate pathogens and symbionts.Mesh:
Year: 2002 PMID: 11893328 DOI: 10.1016/s0092-8674(02)00665-7
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582