Literature DB >> 11893191

Synthesis of marine sponge bisindole alkaloids dihydrohamacanthins.

Fumiko Y Miyake1, Kenichi Yakushijin, David A Horne.   

Abstract

[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.

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Year:  2002        PMID： 11893191     DOI： 10.1021/ol020002j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  A strategy for the total synthesis of dragmacidin E. Construction of the core ring system.

Authors:  Raymond J Huntley; Raymond L Funk
Journal:  Org Lett       Date:  2006-10-12       Impact factor: 6.005

2.  Bisindole Alkaloids from a New Zealand Deep-Sea Marine Sponge Lamellomorpha strongylata.

Authors:  Kavita Ragini; Andrew M Piggott; Peter Karuso
Journal:  Mar Drugs       Date:  2019-12-04       Impact factor: 5.118

3.  Monoindole alkaloids from a marine sponge Spongosorites sp.

Authors:  Baoquan Bao; Ping Zhang; Yoonmi Lee; Jongki Hong; Chong-O Lee; Jee H Jung
Journal:  Mar Drugs       Date:  2007-06-25       Impact factor: 5.118

4.  Marine derived hamacanthins as lead for the development of novel PDGFRβ protein kinase inhibitors.

Authors:  Boris Pinchuk; Eugen Johannes; Sheraz Gul; Joachim Schlosser; Christoph Schaechtele; Frank Totzke; Christian Peifer
Journal:  Mar Drugs       Date:  2013-08-26       Impact factor: 5.118
  4 in total

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