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Literature DB >> 11892040

Viral rhinitis.

Abstract

Viral rhinitis is a common, morbid, and costly malady, often complicated by otitis media, sinusitis, and asthma. Current therapies are relatively ineffective and aimed at reducing symptoms rather than moderating underlying mechanisms. Nasal elevations of proinflammatory cytokines track symptom expression during viral rhinitis, and it is hypothesized that these chemicals orchestrate a common response to infection with many different viruses that cause rhinitis. Also, recent evidence supports a role for neurogenic inflammation in the development of complications. Future studies should dissect the role of proinflammatory cytokines and neuropeptides in the expression of symptoms, signs, pathophysiologies, and complications of viral rhinitis.

Entities: Disease

Mesh：

Substances：

Year: 2001 PMID： 11892040 DOI： 10.1007/s11882-001-0009-3

Source DB: PubMed Journal: Curr Allergy Asthma Rep ISSN： 1529-7322 Impact factor: 4.806

44 in total

1. A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers.

Authors: P G Higgins; G I Barrow; D A Tyrrell
Journal: Antiviral Res Date: 1990-12 Impact factor: 5.970

2. Effect of leukotriene D4 on nasal mucosal blood flow, nasal airway resistance and nasal secretion in humans.

Authors: H Bisgaard; P Olsson; M Bende
Journal: Clin Allergy Date: 1986-07

3. Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus.

Authors: W J Doyle; D P Skoner; C M Alper; G Allen; S A Moody; J T Seroky; F G Hayden
Journal: J Infect Dis Date: 1998-05 Impact factor: 5.226

4. Effect of intranasal challenge with interleukin-6 on upper airway symptomatology and physiology in allergic and nonallergic patients.

Authors: D A Gentile; J Yokitis; B L Angelini; W J Doyle; D P Skoner
Journal: Ann Allergy Asthma Immunol Date: 2001-05 Impact factor: 6.347

5. The role of cytokines in the behavioral responses to endotoxin and influenza virus infection in mice: effects of acute and chronic administration of the interleukin-1-receptor antagonist (IL-1ra).

Authors: A H Swiergiel; G N Smagin; L J Johnson; A J Dunn
Journal: Brain Res Date: 1997-11-21 Impact factor: 3.252

6. Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus.

Authors: Y W Tang; B S Graham
Journal: J Clin Invest Date: 1994-11 Impact factor: 14.808

7. Increased interleukin-6 levels in nasal lavage samples following experimental influenza A virus infection.

Authors: D Gentile; W Doyle; T Whiteside; P Fireman; F G Hayden; D Skoner
Journal: Clin Diagn Lab Immunol Date: 1998-09

8. A longitudinal study of respiratory viruses and bacteria in the etiology of acute otitis media with effusion.

Authors: F W Henderson; A M Collier; M A Sanyal; J M Watkins; D L Fairclough; W A Clyde; F W Denny
Journal: N Engl J Med Date: 1982-06-10 Impact factor: 91.245

9. Severity of respiratory syncytial virus disease related to type and genotype of virus and to cytokine values in nasopharyngeal secretions.

Authors: A Hornsleth; B Klug; M Nir; J Johansen; K S Hansen; L S Christensen; L B Larsen
Journal: Pediatr Infect Dis J Date: 1998-12 Impact factor: 2.129

10. Development of interleukin 6 and tumor necrosis factor alpha activity in nasopharyngeal secretions of infants and children during infection with respiratory syncytial virus.

Authors: K Matsuda; H Tsutsumi; Y Okamoto; C Chiba
Journal: Clin Diagn Lab Immunol Date: 1995-05

5 in total

Viral rhinitis.

1. A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers.

2. Effect of leukotriene D4 on nasal mucosal blood flow, nasal airway resistance and nasal secretion in humans.

3. Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus.

4. Effect of intranasal challenge with interleukin-6 on upper airway symptomatology and physiology in allergic and nonallergic patients.

5. The role of cytokines in the behavioral responses to endotoxin and influenza virus infection in mice: effects of acute and chronic administration of the interleukin-1-receptor antagonist (IL-1ra).

6. Anti-IL-4 treatment at immunization modulates cytokine expression, reduces illness, and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus.

7. Increased interleukin-6 levels in nasal lavage samples following experimental influenza A virus infection.

8. A longitudinal study of respiratory viruses and bacteria in the etiology of acute otitis media with effusion.

9. Severity of respiratory syncytial virus disease related to type and genotype of virus and to cytokine values in nasopharyngeal secretions.

10. Development of interleukin 6 and tumor necrosis factor alpha activity in nasopharyngeal secretions of infants and children during infection with respiratory syncytial virus.

1. Congenital CSF Rhinorrhoea sans Encephalocoele, sans Trauma, sans Tumour.

2. How does rhinovirus cause the common cold cough?

Review 3. Modulation of airway hyperresponsiveness by rhinovirus exposure.

4. Oxymetazoline inhibits and resolves inflammatory reactions in human neutrophils.

5. Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells.