PURPOSE: To investigate blood perfusion of vertebral lesions using dynamic Gd-DTPA-enhanced MRI. MATERIALS AND METHODS: Dynamic MR studies were performed for cases of acute compression fracture, chronic compression fracture, metastatic vertebral lesions with or without compression fracture. A total of 42 patients (71 vertebral segments) were included. Five types of time-intensity curves (TICs) were defined as: nearly no enhancement (type A), slow enhancement (type B), a rapid contrast wash-in followed by an equilibrium phase (type C), a rapid contrast wash-in followed by early wash-out (type D), and a rapid contrast wash-in with a second slower-rising slope (type E). RESULTS: Metastatic vertebral lesions with or without fracture had a higher peak enhancement percentage and steeper enhancement slope than those of chronic compression fracture, but had no difference as compared to those of acute compression fracture. The type D curve had high positive predictive value for metastatic group (100%), and the type E curve had high positive predictive value for benign compression fracture (85.7%). CONCLUSION: Type D and E curves are valuable in the differentiation of benign and malignant vertebral lesions.
PURPOSE: To investigate blood perfusion of vertebral lesions using dynamic Gd-DTPA-enhanced MRI. MATERIALS AND METHODS: Dynamic MR studies were performed for cases of acute compression fracture, chronic compression fracture, metastatic vertebral lesions with or without compression fracture. A total of 42 patients (71 vertebral segments) were included. Five types of time-intensity curves (TICs) were defined as: nearly no enhancement (type A), slow enhancement (type B), a rapid contrast wash-in followed by an equilibrium phase (type C), a rapid contrast wash-in followed by early wash-out (type D), and a rapid contrast wash-in with a second slower-rising slope (type E). RESULTS:Metastatic vertebral lesions with or without fracture had a higher peak enhancement percentage and steeper enhancement slope than those of chronic compression fracture, but had no difference as compared to those of acute compression fracture. The type D curve had high positive predictive value for metastatic group (100%), and the type E curve had high positive predictive value for benign compression fracture (85.7%). CONCLUSION: Type D and E curves are valuable in the differentiation of benign and malignant vertebral lesions.
Authors: N R Khadem; S Karimi; K K Peck; Y Yamada; E Lis; J Lyo; M Bilsky; H A Vargas; A I Holodny Journal: AJNR Am J Neuroradiol Date: 2012-05-03 Impact factor: 3.825
Authors: Arda Kayhan; Cheng Yang; Fatma Nur Soylu; Hatice Lakadamyalı; Ila Sethi; Gregory Karczmar; Walter Stadler; Aytekin Oto Journal: World J Radiol Date: 2011-10-28