PURPOSE: To elucidate the ability of 3He-MRI to detect ventilation defects in lung transplant recipients, 3He-MRI was compared to CT for concordance. MATERIALS AND METHODS: We examined 14 lung recipients using 3He-MRI on a 1.5 T MR scanner. CT served as a reference method. Up to four representative ventilation defects were defined for each lung on 3He-MRI and compared to corresponding areas on CT. RESULTS: Altogether, 59 representative ventilation defects were defined on 3He-MRI. Plausible CT correlates were found for 29 ventilation defects; less plausible CT correlates were found for eight defects. In 22 defects (37%) no corresponding CT changes were detected. CT demonstrated correlates for ventilation defects seen on 3He-MRI in only 63% of the cases. CONCLUSION: 3He-MRI yields a clear increase in the number of detected ventilation defects compared to CT. This may have an important impact on the early detection of bronchiolitis obliterans in lung transplant recipients.
PURPOSE: To elucidate the ability of 3He-MRI to detect ventilation defects in lung transplant recipients, 3He-MRI was compared to CT for concordance. MATERIALS AND METHODS: We examined 14 lung recipients using 3He-MRI on a 1.5 T MR scanner. CT served as a reference method. Up to four representative ventilation defects were defined for each lung on 3He-MRI and compared to corresponding areas on CT. RESULTS: Altogether, 59 representative ventilation defects were defined on 3He-MRI. Plausible CT correlates were found for 29 ventilation defects; less plausible CT correlates were found for eight defects. In 22 defects (37%) no corresponding CT changes were detected. CT demonstrated correlates for ventilation defects seen on 3He-MRI in only 63% of the cases. CONCLUSION:3He-MRI yields a clear increase in the number of detected ventilation defects compared to CT. This may have an important impact on the early detection of bronchiolitis obliterans in lung transplant recipients.
Authors: Klaus Kurt Gast; Julia Zaporozhan; Sebastian Ley; Alexander Biedermann; Frank Knitz; Balthasar Eberle; Joerg Schmiedeskamp; Claus-Peter Heussel; Eckhard Mayer; Wolfgang Günter Schreiber; Manfred Thelen; Hans-Ulrich Kauczor Journal: Eur Radiol Date: 2003-10-16 Impact factor: 5.315
Authors: James H Holmes; Rafael L O'Halloran; Ethan K Brodsky; Youngkyoo Jung; Walter F Block; Sean B Fain Journal: Magn Reson Med Date: 2008-05 Impact factor: 4.668
Authors: Colm J McMahon; Jonathan D Dodd; Catherine Hill; Neil Woodhouse; Jim M Wild; Stan Fichele; Charles G Gallagher; Stephen J Skehan; Edwin J R van Beek; James B Masterson Journal: Eur Radiol Date: 2006-07-27 Impact factor: 5.315
Authors: Emily F Fishman; James D Quirk; Stuart C Sweet; Jason C Woods; David S Gierada; Mark S Conradi; Marilyn J Siegel; Dmitriy A Yablonskiy Journal: Pediatr Transplant Date: 2017-01-24
Authors: Lucia Flors; John P Mugler; Eduard E de Lange; Grady W Miller; Jaime F Mata; Nick Tustison; Iulian C Ruset; F William Hersman; Talissa A Altes Journal: J Thorac Imaging Date: 2016-09 Impact factor: 3.000
Authors: Barbara A Lutey; Stephen S Lefrak; Jason C Woods; Tariq Tanoli; James D Quirk; Adil Bashir; Dmitriy A Yablonskiy; Mark S Conradi; Seth T Bartel; Thomas K Pilgram; Joel D Cooper; David S Gierada Journal: Radiology Date: 2008-08 Impact factor: 11.105