| Literature DB >> 11890780 |
Song Ye1, Zheng-Zheng Huang, Chun-An Xia, Yong Tang, Li-Xin Dai.
Abstract
A newly designed chiral sulfonium allylide, generated in situ from the corresponding sulfonium salt in the presence of KOBu(t), reacted with alpha,beta-unsaturated esters, ketones, amides, and nitriles to afford trans-2-silylvinyl-trans-3-substituted cyclopropyl esters, ketones, amides, and nitriles with outstanding diastereoselectivity and excellent enantioselectivity in good to high yields. A mechanistic rationale is proposed.Entities:
Mesh：
Substances：
Year: 2002 PMID： 11890780 DOI： 10.1021/ja0172969
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419