Literature DB >> 11887251

[Prenatal manifestation of a congenital glioblastoma - Case report].

S Schindelmann1, G Sandner, N Harbeck, G Debus.   

Abstract

In prenatal ultrasound screening, internal hydrocephalus and intracranial bleeding of the fetus are considered as primary diagnostic signs for a congenital brain tumor. We report the prenatal sonographic diagnosis of a congenital glioblastoma due to acute fetal internal hydrocephalus in the 37th week of gestation. After birth, the tumor's hyperechoic appearance on ultrasound was indistinguishable from intracranial bleeding. Diagnosis of a congenital glioblastoma (WHO stage IV) was confirmed by subtotal tumorectomy in the 9th week of life. In the international literature, only 6 cases of prenatally diagnosed glioblastomas have so far been reported, all of which associated with sonographically diagnosed fetal hydrocephalus. Further sonographic signs for a brain tumor are the tumor mass itself, a polyhydramnion, enlarged biparietal diameters and head circumferences, as well as suspected intracranial bleeding.

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Year:  2002        PMID: 11887251     DOI: 10.1055/s-2002-20946

Source DB:  PubMed          Journal:  Z Geburtshilfe Neonatol        ISSN: 0948-2393            Impact factor:   0.685


  1 in total

1.  Congenital glioblastoma multiforme with abnormal vascularity presenting as intracranial hemorrhage in prenatal ultrasound.

Authors:  Manfred Sell; Sabine Huber-Schumacher; Frank K H van Landeghem
Journal:  Childs Nerv Syst       Date:  2006-05-04       Impact factor: 1.475

  1 in total

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