Literature DB >> 11875198

Proteins: paradigms of complexity.

Hans Frauenfelder1.   

Abstract

Proteins are the working machines of living systems. Directed by the DNA, of the order of a few hundred building blocks, selected from 20 different amino acids, are covalently linked into a linear polypeptide chain. In the proper environment, the chain folds into the working protein, often a globule of linear dimensions of a few nanometers. The biologist considers proteins units from which living systems are built. Many physical scientists look at them as systems in which the laws of complexity can be studied better than anywhere else. Some of the results of such studies will be sketched.

Mesh:

Substances:

Year:  2002        PMID: 11875198      PMCID: PMC128564          DOI: 10.1073/pnas.012579999

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  6 in total

1.  Proteomics. Proteomics in genomeland.

Authors:  S Fields
Journal:  Science       Date:  2001-02-16       Impact factor: 47.728

2.  The energy landscapes and motions of proteins.

Authors:  H Frauenfelder; S G Sligar; P G Wolynes
Journal:  Science       Date:  1991-12-13       Impact factor: 47.728

3.  Protein states and proteinquakes.

Authors:  A Ansari; J Berendzen; S F Bowne; H Frauenfelder; I E Iben; T B Sauke; E Shyamsunder; R D Young
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

4.  Hole burning spectroscopy and physics of proteins.

Authors:  J Friedrich
Journal:  Methods Enzymol       Date:  1995       Impact factor: 1.600

5.  The role of structure, energy landscape, dynamics, and allostery in the enzymatic function of myoglobin.

Authors:  H Frauenfelder; B H McMahon; R H Austin; K Chu; J T Groves
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-20       Impact factor: 11.205

6.  Dynamics of ligand binding to myoglobin.

Authors:  R H Austin; K W Beeson; L Eisenstein; H Frauenfelder; I C Gunsalus
Journal:  Biochemistry       Date:  1975-12-02       Impact factor: 3.162

  6 in total
  10 in total

1.  Self-organized complexity in the physical, biological, and social sciences.

Authors:  Donald L Turcotte; John B Rundle
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-19       Impact factor: 11.205

2.  Evidence of discrete substates and unfolding pathways in green fluorescent protein.

Authors:  Giancarlo Baldini; Fabio Cannone; Giuseppe Chirico; Maddalena Collini; Barbara Campanini; Stefano Bettati; Andrea Mozzarelli
Journal:  Biophys J       Date:  2006-12-01       Impact factor: 4.033

3.  How a vicinal layer of solvent modulates the dynamics of proteins.

Authors:  Canan Atilgan; Ayse Ozlem Aykut; Ali Rana Atilgan
Journal:  Biophys J       Date:  2007-09-07       Impact factor: 4.033

4.  Localizing frustration in native proteins and protein assemblies.

Authors:  Diego U Ferreiro; Joseph A Hegler; Elizabeth A Komives; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-05       Impact factor: 11.205

5.  Protein Frustratometer 2: a tool to localize energetic frustration in protein molecules, now with electrostatics.

Authors:  R Gonzalo Parra; Nicholas P Schafer; Leandro G Radusky; Min-Yeh Tsai; A Brenda Guzovsky; Peter G Wolynes; Diego U Ferreiro
Journal:  Nucleic Acids Res       Date:  2016-04-29       Impact factor: 16.971

6.  Stretching the immunoglobulin 27 domain of the titin protein: the dynamic energy landscape.

Authors:  Nathan Duff; N-H Duong; Daniel J Lacks
Journal:  Biophys J       Date:  2006-08-11       Impact factor: 4.033

7.  Side chain dynamics monitored by 13C-13C cross-relaxation.

Authors:  Klaartje Houben; Rolf Boelens
Journal:  J Biomol NMR       Date:  2004-06       Impact factor: 2.835

8.  Effect of Calcium Ion Removal, Ionic Strength, and Temperature on the Conformation Change in Calmodulin Protein at Physiological pH.

Authors:  Sunita Negi
Journal:  J Biophys       Date:  2014-12-09

9.  Scale-free flow of life: on the biology, economics, and physics of the cell.

Authors:  Alexei Kurakin
Journal:  Theor Biol Med Model       Date:  2009-05-05       Impact factor: 2.432

10.  Detecting repetitions and periodicities in proteins by tiling the structural space.

Authors:  R Gonzalo Parra; Rocío Espada; Ignacio E Sánchez; Manfred J Sippl; Diego U Ferreiro
Journal:  J Phys Chem B       Date:  2013-07-05       Impact factor: 2.991

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.