Literature DB >> 118744

Specific interaction of human Tamm-Horsfall gylcoprotein with leucoagglutinin, a lectin from Phaseolus vulgaris (red kidney bean).

F Serafini-Cessi, C Franceschi, S Sperti.   

Abstract

Human Tamm-Horsfall glycoprotein inhibits lymphocyte transformation induced by leucoagglutinin and haemagglutinin from Phaseolus vulgaris (red kidney bean). The glycoprotein interacts with the two lectins, giving insoluble precipitates. The interaction with leucoagglutinin is highly specific, and the shape of the precipitin curve is that of an antigen-antibody reaction; precipitation is specifically inhibited by N-acetyl-D-galactosamine. Results are discussed, and it is suggested that inhibition of lymphocyte transformation is due to competition between human Tamm-Horsfall glycoprotein and carbohydrate receptors on lymphocytes for the two lectins. The interaction between human Tamm-Horsfall glycoprotein and Phaseolus vulgaris lectins has been used to develop a one-step procedure for the separation of the two lectins by affinity chromatography on (human Tamm-Horsfall-glycoprotein)-Sepharose.

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Year:  1979        PMID: 118744      PMCID: PMC1161569          DOI: 10.1042/bj1830381

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  30 in total

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Authors:  R G SPIRO
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Authors:  C E CORNELIUS; A S MIA; S ROSENFELD
Journal:  Invest Urol       Date:  1965-03

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4.  Extensive homology between the subunits of the phytohemagglutinin mitogenic proteins derived from Phaseolus vulgaris.

Authors:  J B Miller; R Hsu; R Heinrikson; S Yachnin
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

5.  Disk electrophoresis of basic proteins and peptides on polyacrylamide gels.

Authors:  R A REISFELD; U J LEWIS; D E WILLIAMS
Journal:  Nature       Date:  1962-07-21       Impact factor: 49.962

6.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

7.  Characterization and separation of an inhibitor of viral hemagglutination present in urine.

Authors:  I TAMM; F L HORSFALL
Journal:  Proc Soc Exp Biol Med       Date:  1950-05

8.  The interaction of nonmitogenic and mitogenic lectins with T lymphocytes: association of cellular receptor sites.

Authors:  U Hellström; M L Dillner; S Hammarström; P Perlmann
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

9.  Inhibition of phytohemagglutinin-induced lymphocyte transformation by globulins; lack of correlation with phytohemagglutinin precipitation by serum proteins.

Authors:  S Yachnin
Journal:  J Immunol       Date:  1972-03       Impact factor: 5.422

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Authors:  F J Bloomfield; D R Dunstan; C L Foster; F Serafini-Cessi; R D Marshall
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

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  10 in total

1.  Ectopic expression of N-acetylglucosaminyltransferase III in transgenic hepatocytes disrupts apolipoprotein B secretion and induces aberrant cellular morphology with lipid storage.

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Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

2.  Properties of a glycopeptide isolated from human Tamm-Horsfall glycoprotein. Interaction with leucoagglutinin and anti-(human Tamm-Horsfall glycoprotein) antibodies.

Authors:  A Abbondanza; C Franceschi; F Licastro; F Serafini-Cessi
Journal:  Biochem J       Date:  1980-05-01       Impact factor: 3.857

3.  Mitogenic leukoagglutinin from Phaseolus vulgaris binds to a pentasaccharide unit in N-acetyllactosamine-type glycoprotein glycans.

Authors:  S Hammarström; M L Hammarström; G Sundblad; J Arnarp; J Lönngren
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

4.  Processing of N-linked oligosaccharides from precursor- to mature-form herpes simplex virus type 1 glycoprotein gC.

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Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

Review 5.  N-Glycans carried by Tamm-Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases.

Authors:  Franca Serafini-Cessi; Angela Monti; Daniela Cavallone
Journal:  Glycoconj J       Date:  2005-11       Impact factor: 3.009

6.  Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells.

Authors:  Yau Sang Chan; Jack Ho Wong; Evandro Fei Fang; Wenliang Pan; Tzi Bun Ng
Journal:  PLoS One       Date:  2012-06-14       Impact factor: 3.240

Review 7.  Tamm-Horsfall Protein is a Potent Immunomodulatory Molecule and a Disease Biomarker in the Urinary System.

Authors:  Tsai-Hung Wu; Ko-Jen Li; Chia-Li Yu; Chang-Youh Tsai
Journal:  Molecules       Date:  2018-01-22       Impact factor: 4.411

8.  The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H.

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Journal:  J Cell Mol Med       Date:  2021-03-31       Impact factor: 5.310

9.  SDS-PAGE-Based Quantitative Assay for Screening of Kidney Stone Disease.

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Journal:  Biol Proced Online       Date:  2009-05-15       Impact factor: 3.244

10.  Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response.

Authors:  Céline Schaeffer; Stefania Merella; Elena Pasqualetto; Dejan Lazarevic; Luca Rampoldi
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  10 in total

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