Literature DB >> 11872315

A review of the anatomy of the upper airway in early infancy and its possible relevance to SIDS.

S L Tonkin1, T R Gunn, L Bennet, S A Vogel, A J Gunn.   

Abstract

BACKGROUND: Since the danger of prone sleeping in the first 6 months of life has been publicised, there has been a dramatic and consistent reduction in the incidence of sudden infant death syndrome (SIDS). However, unexpected infant deaths and apparent life-threatening events (ALTEs) continue to occur that are clearly not associated with known epidemiological risk factors. AIMS: To review the unique features of the anatomy and function of the upper airway of the young infant which contribute to increased vulnerability to hypoxia in this age group. We discuss the clinical identification of those infants at risk of obstruction or restriction of the upper airway and the management of the 'at risk' infant.
CONCLUSIONS: In the era after the "back to sleep" campaigns, it is likely that an increasing proportion of cases of ALTEs and SIDS will be related to obstruction or limitation of upper airway size leading to sleep hypoxia/asphyxia. This type of problem may be anticipated by evaluation and investigation of infants with signs or a clinical history consistent with possible upper respiratory tract compromise, including micrognathia.

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Mesh:

Year:  2002        PMID: 11872315     DOI: 10.1016/s0378-3782(01)00242-0

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN: 0378-3782            Impact factor:   2.079


  6 in total

1.  Nasal versus oronasal raised volume forced expirations in infants--a real physiologic challenge.

Authors:  Mohy G Morris
Journal:  Pediatr Pulmonol       Date:  2012-02-10

2.  The Ogival Palate: A New Risk Marker of Sudden Unexpected Death in Infancy?

Authors:  Mathilde Ducloyer; Matthieu Wargny; Charlotte Medo; Pierre-Antoine Gourraud; Renaud Clement; Karine Levieux; Christèle Gras-Le Guen; Pierre Corre; Caroline Rambaud
Journal:  Front Pediatr       Date:  2022-04-18       Impact factor: 3.569

3.  Potential Mechanisms of Failure in the Sudden Infant Death Syndrome.

Authors:  Ronald M Harper; Hannah C Kinney
Journal:  Curr Pediatr Rev       Date:  2010-02-01

4.  Sudden deaths in adult-worn baby carriers: 19 cases.

Authors:  J Bergounioux; C Madre; A Crucis-Armengaud; E Briand-Huchet; A P Michard-Lenoir; H Patural; S Dauger; S Renolleau; A M Teychéne; S Henry; D Biarent; C Robin; E Werner; C Rambaud
Journal:  Eur J Pediatr       Date:  2015-07-15       Impact factor: 3.183

Review 5.  A perspective on SIDS pathogenesis. the hypotheses: plausibility and evidence.

Authors:  Paul N Goldwater
Journal:  BMC Med       Date:  2011-05-27       Impact factor: 8.775

Review 6.  Gut Microbiota and Immunity: Possible Role in Sudden Infant Death Syndrome.

Authors:  Paul N Goldwater
Journal:  Front Immunol       Date:  2015-06-03       Impact factor: 7.561

  6 in total

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