Literature DB >> 11871610

Numerical analysis of flow through a severely stenotic carotid artery bifurcation.

J S Stroud1, S A Berger, D Saloner.   

Abstract

The results of computational simulations may supplement MR and other in vivo diagnostic techniques to provide an accurate picture of the hemodynamics in particular vessels, which may help demonstrate the risks of embolism or plaque rupture posed by particular plaque deposits. In this study, a model based on an endarterectomy specimen of the plaque in a carotid bifurcation was examined. The flow conditions include steady flow at Reynolds numbers of 300, 600, and 900 as well as unsteady pulsatile flow. Both dynamic pressure and wall shear stress are very high, with shear values up to 70 N/m2, proximal to the stenosis throat in the internal carotid artery, and both vary significantly through the flow cycle. The wall shear stress gradient is also strong along the throat. Vortex shedding is observed downstream of the most severe occlusion. Two turbulence models, the Chien and Goldberg varieties of k-epsilon, are tested and evaluated for their relevance in this geometry. The Chien model better captures phenomena such as vortex shedding. The flow distal to stenosis is likely transitional, so a model that captures both laminar and turbulent behavior is needed.

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Year:  2002        PMID: 11871610     DOI: 10.1115/1.1427042

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  30 in total

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5.  Quantifying effects of plaque structure and material properties on stress distributions in human atherosclerotic plaques using 3D FSI models.

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Journal:  J Biomech Eng       Date:  2005-12       Impact factor: 2.097

6.  A simplified murine intimal hyperplasia model founded on a focal carotid stenosis.

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7.  Numerical modeling of the flow in intracranial aneurysms: prediction of regions prone to thrombus formation.

Authors:  V L Rayz; L Boussel; M T Lawton; G Acevedo-Bolton; L Ge; W L Young; R T Higashida; D Saloner
Journal:  Ann Biomed Eng       Date:  2008-09-12       Impact factor: 3.934

8.  Possibility of atherosclerosis in an arterial bifurcation model.

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9.  Transitional Flow in a Cylindrical Flow Chamber for Studies at the Cellular Level.

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Review 10.  Systems Analysis of Thrombus Formation.

Authors:  Scott L Diamond
Journal:  Circ Res       Date:  2016-04-29       Impact factor: 17.367

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