| Literature DB >> 11869895 |
Michael Schebesta1, Barry Heavey, Meinrad Busslinger.
Abstract
Significant progress has recently been made in our understanding of how transcription factors such as PU.1, Notch1, E2A, EBF, Pax5, Bcl6, Blimp1 and XBP1 control different developmental decisions during the onset and terminal phase of B-lymphopoiesis. One emerging theme is that negative regulatory networks play an important role in suppressing alternative gene programs and their corresponding cell fates throughout B-cell development.Entities:
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Year: 2002 PMID: 11869895 DOI: 10.1016/s0952-7915(02)00324-2
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486