Literature DB >> 1186898

Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39.

J Frere, J Ghuysen, J Degelaen, A Loffet, H R Perkins.   

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Year:  1975        PMID: 1186898     DOI: 10.1038/258168a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  14 in total

1.  The exocellular DD-carboxypeptidase-endopeptidase of Streptomyces albus G. Interaction with beta-lactam antibiotics.

Authors:  J M Frère; F Geurts; J M Ghuysen
Journal:  Biochem J       Date:  1978-12-01       Impact factor: 3.857

Review 2.  Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.

Authors:  Colette Goffin; Jean-Marie Ghuysen
Journal:  Microbiol Mol Biol Rev       Date:  2002-12       Impact factor: 11.056

3.  A point mutation leads to altered product specificity in beta-lactamase catalysis.

Authors:  E R Lewis; K M Winterberg; A L Fink
Journal:  Proc Natl Acad Sci U S A       Date:  1997-01-21       Impact factor: 11.205

4.  Mode of interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidase--transpeptidase from Streptomyces R39.

Authors:  N Fuad; J M Frère; J M Ghuysen; C Duez; M Iwatsubo
Journal:  Biochem J       Date:  1976-06-01       Impact factor: 3.857

5.  Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.

Authors:  J M Ghuysen; J M Frère; M Leyh-Bouille; M Nguyen-Distèche; J Coyette
Journal:  Biochem J       Date:  1986-04-01       Impact factor: 3.857

6.  Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases.

Authors:  R R Yocum; D J Waxman; J R Rasmussen; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

7.  Importance of the His-298 residue in the catalytic mechanism of the Streptomyces R61 extracellular DD-peptidase.

Authors:  A M Hadonou; M Jamin; M Adam; B Joris; J Dusart; J M Ghuysen; J M Frère
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

8.  The exocellular beta-lactamase of Streptomyces albus G. Purification, properties and comparison with the exocellular DD-carboxypeptidase.

Authors:  C Duez; J M Frère; D Klein; M Noël; J M Ghuysen; L Delcambe; L Dierickx
Journal:  Biochem J       Date:  1981-01-01       Impact factor: 3.857

9.  Effects of nucleophiles on the breakdown of the benzylpenicilloyl-enzyme complex EI formed between benzylpenicillin and the exocellular DD-carboxypeptidase--transpeptiase of Streptomyces strain R61.

Authors:  A Marquet; J M Frère; J M Ghuysen; A Loffet
Journal:  Biochem J       Date:  1979-03-01       Impact factor: 3.857

10.  Simultaneous release of penicilloic acid and phenylacetyl glycine by penicillin-binding proteins 5 and 6 of Escherichia coli.

Authors:  H Amanuma; J L Strominger
Journal:  J Bacteriol       Date:  1984-11       Impact factor: 3.490

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