Literature DB >> 11866012

Management of lower respiratory tract infections by French general practitioners: the AIR II study. Analyse Infections Respiratoires.

C Raherison1, P Peray, R Poirier, P Romand, J P Grignet, P Arsac, A Taytard, J P Daures.   

Abstract

The Analyse Infections Respiratoires (AIR) II study is a prospective, multicentre survey of the management of lower respiratory tract infections in patients aged 15-65 yrs by general practitioners (GPs) in France. To obtain real-time data recording, practitioners were required to submit an anonymous copy of their drug prescriptions. They were then interviewed over the telephone about the patients' sociodemographic data, signs and symptoms, as well as their presumptive diagnosis and the investigations they had decided upon. GPs (n=3,144) reported 5,469 evaluable cases. Pneumonia accounted for 9.6% of diagnoses, acute exacerbations of chronic bronchitis 14.9% and acute bronchitis 72.5%. The symptomatology covered an extremely wide range of clinical features, which, although statistically different in terms of incidence, overlapped to a large extent across diagnoses. By contrast, hospitalization, investigations or referral to a specialist were much more prevalent in pneumonia, although still very infrequent in general terms (0.5, 1.2 and 10.8%, respectively). Antibiotics were prescribed in 96.5% of patients, with minor differences between diagnoses. However, other medications such as nonsteroid, anti-inflammatory drugs, steroids, nonspecific antitussives and bronchial liquefiers accounted for two-thirds of the prescriptions. This study demonstrates the lower respiratory tract infections encountered by general practitioners are usually mild. However, antibiotic prescription was more systematic than in previous studies and the prescription of nonspecific symptomatic treatments was twice as frequent. General practitioners did not perform additional examinations or refer on a regular basis. There was a high prescription rate for symptomatic treatment.

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Year:  2002        PMID: 11866012     DOI: 10.1183/09031936.02.00219102

Source DB:  PubMed          Journal:  Eur Respir J        ISSN: 0903-1936            Impact factor:   16.671


  11 in total

1.  A diagnostic rule for the aetiology of lower respiratory tract infections as guidance for antimicrobial treatment.

Authors:  A Willy Graffelman; Arie Knuistingh Neven; Saskia le Cessie; Aloys C M Kroes; Machiel P Springer; Peterhans J van den Broek
Journal:  Br J Gen Pract       Date:  2004-01       Impact factor: 5.386

2.  Pathogens involved in lower respiratory tract infections in general practice.

Authors:  A Willy Graffelman; Arie Knuistingh Neven; Saskia le Cessie; Aloys C M Kroes; Machiel P Springer; Peterhans J van den Broek
Journal:  Br J Gen Pract       Date:  2004-01       Impact factor: 5.386

Review 3.  Diagnostic value of C reactive protein in infections of the lower respiratory tract: systematic review.

Authors:  Victor van der Meer; Arie Knuistingh Neven; Peterhans J van den Broek; Willem J J Assendelft
Journal:  BMJ       Date:  2005-06-24

4.  Non-steroidal Anti-inflammatory Drugs may Worsen the Course of Community-Acquired Pneumonia: A Cohort Study.

Authors:  Damien Basille; Nathalie Plouvier; Charlotte Trouve; Pierre Duhaut; Claire Andrejak; Vincent Jounieaux
Journal:  Lung       Date:  2016-12-22       Impact factor: 2.584

5.  Determining factors in the prescription of moxifloxacin in exacerbations of chronic bronchitis in the primary-care setting.

Authors:  Marc Miravitlles; Carles Llor
Journal:  Clin Drug Investig       Date:  2007       Impact factor: 2.859

6.  Procalcitonin versus C-reactive protein for predicting pneumonia in adults with lower respiratory tract infection in primary care.

Authors:  Anette Holm; Svend S Pedersen; Joergen Nexoe; Niels Obel; Lars P Nielsen; Ole Koldkjaer; Court Pedersen
Journal:  Br J Gen Pract       Date:  2007-07       Impact factor: 5.386

7.  Aetiology and prediction of pneumonia in lower respiratory tract infection in primary care.

Authors:  Anette Holm; Joergen Nexoe; Lene A Bistrup; Svend S Pedersen; Niels Obel; Lars P Nielsen; Court Pedersen
Journal:  Br J Gen Pract       Date:  2007-07       Impact factor: 5.386

8.  Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care? Study protocol for a randomised controlled trial.

Authors:  Harriet E Downing; Fran Carroll; Sara T Brookes; Sandra Hollinghurst; David Timmins; Elizabeth Orton; Kay Wang; Denise Kendrick; Paul Little; Mike V Moore; Anthony Harnden; Matthew Thompson; Margaret T May; Alastair D Hay
Journal:  Trials       Date:  2015-03-07       Impact factor: 2.279

Review 9.  [Definition of low respiratory tract infections].

Authors:  B Housset
Journal:  Med Mal Infect       Date:  2006-07-11       Impact factor: 2.152

Review 10.  Outpatient antibiotic use and prevalence of antibiotic-resistant pneumococci in France and Germany: a sociocultural perspective.

Authors:  Stephan Harbarth; Werner Albrich; Christian Brun-Buisson
Journal:  Emerg Infect Dis       Date:  2002-12       Impact factor: 6.883

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