Literature DB >> 11863014

Ethical issues in HIV vaccine trials in South Africa.

C Slack1, G Lindegger, E Vardas, L Richter, A Strode, D Wassenaar.   

Abstract

In this review we describe the ethical issues central to local and international debates about HIV vaccine trials. These issues include the physiological and psycho-social risks of trial participation, the preventative interventions to be provided to participants, access to treatment for participants who seroconvert, access to an effective vaccine after the trial, the role of placebo-controlled trials, and obtaining informed consent.

Entities:  

Keywords:  Biomedical and Behavioral Research; International Ethical Guidelines for Biomedical Research Involving Human Subjects; UNAIDS

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Year:  2000        PMID： 11863014

Source DB:  PubMed          Journal:  S Afr J Sci        ISSN： 0038-2353            Impact factor:   2.197


  4 in total

Review 1.  A model designed to enhance informed consent: experiences from the HIV prevention trials network.

Authors:  Cynthia Woodsong; Quarraisha Abdool Karim
Journal:  Am J Public Health       Date:  2005-03       Impact factor: 9.308

2.  Convergent ethical issues in HIV/AIDS, tuberculosis and malaria vaccine trials in Africa: Report from the WHO/UNAIDS African AIDS Vaccine Programme's Ethics, Law and Human Rights Collaborating Centre consultation, 10-11 February 2009, Durban, South Africa.

Authors:  Nicole Mamotte; Douglas Wassenaar; Jennifer Koen; Zaynab Essack
Journal:  BMC Med Ethics       Date:  2010-03-09       Impact factor: 2.652

3.  Sexual risk behaviour of the first cohort undergoing screening for enrollment into Phase I/II HIV vaccine trials in South Africa.

Authors:  K M Andersson; R M Van Niekerk; L M Niccolai; O N Mlungwana; I M Holdsworth; M Bogoshi; J A McIntyre; G E Gray; E Vardas
Journal:  Int J STD AIDS       Date:  2009-02       Impact factor: 1.359

4.  Anticipated changes in sexual risk behaviour following vaccination with a low-efficacy HIV vaccine: survey results from a South African township.

Authors:  K M Andersson; E Vardas; L M Niccolai; R M Van Niekerk; M M Mogale; I M Holdsworth; M Bogoshi; J A McIntyre; G E Gray
Journal:  Int J STD AIDS       Date:  2012-10       Impact factor: 1.359
  4 in total

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