Literature DB >> 20211030

Convergent ethical issues in HIV/AIDS, tuberculosis and malaria vaccine trials in Africa: Report from the WHO/UNAIDS African AIDS Vaccine Programme's Ethics, Law and Human Rights Collaborating Centre consultation, 10-11 February 2009, Durban, South Africa.

Nicole Mamotte1, Douglas Wassenaar, Jennifer Koen, Zaynab Essack.   

Abstract

BACKGROUND: Africa continues to bear a disproportionate share of the global HIV/AIDS, tuberculosis (TB) and malaria burden. The development and distribution of safe, effective and affordable vaccines is critical to reduce these epidemics. However, conducting HIV/AIDS, TB, and/or malaria vaccine trials simultaneously in developing countries, or in populations affected by all three diseases, is likely to result in numerous ethical challenges.
METHODS: In order to explore convergent ethical issues in HIV/AIDS, TB and malaria vaccine trials in Africa, the Ethics, Law and Human Rights Collaborating Centre of the WHO/UNAIDS African AIDS Vaccine Programme hosted a consultation on the Convergent Ethical Issues in HIV/AIDS, TB and Malaria Vaccine Trials in Africa in Durban, South Africa on the 10-11 February 2009.
RESULTS: Key cross cutting ethical issues were prioritized during the consultation as community engagement; ancillary care obligations; care and treatment; informed consent; and resource sharing.
CONCLUSION: The consultation revealed that while there have been few attempts to find convergence on ethical issues between HIV/AIDS, TB and malaria vaccine trial fields to date, there is much common ground and scope for convergence work between stakeholders in the three fields.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20211030      PMCID: PMC2845591          DOI: 10.1186/1472-6939-11-3

Source DB:  PubMed          Journal:  BMC Med Ethics        ISSN: 1472-6939            Impact factor:   2.652


  16 in total

1.  The ancillary-care responsibilities of medical researchers. An ethical framework for thinking about the clinical care that researchers owe their subjects.

Authors:  Henry S Richardson; Leah Belsky
Journal:  Hastings Cent Rep       Date:  2004 Jan-Feb       Impact factor: 2.683

2.  What makes clinical research in developing countries ethical? The benchmarks of ethical research.

Authors:  Ezekiel J Emanuel; David Wendler; Jack Killen; Christine Grady
Journal:  J Infect Dis       Date:  2004-02-17       Impact factor: 5.226

3.  Towards a science of community engagement.

Authors:  Peter A Newman
Journal:  Lancet       Date:  2006-01-28       Impact factor: 79.321

4.  Beyond the checklist: assessing understanding for HIV vaccine trial participation in South Africa.

Authors:  Graham Lindegger; Cecilia Milford; Catherine Slack; Michael Quayle; Xolani Xaba; Eftyhia Vardas
Journal:  J Acquir Immune Defic Syndr       Date:  2006-12-15       Impact factor: 3.731

Review 5.  Ethical issues in tuberculosis vaccine trials.

Authors:  D E Snider
Journal:  Clin Infect Dis       Date:  2000-06       Impact factor: 9.079

6.  Prevention of tuberculosis in Bacille Calmette-Guérin-primed, HIV-infected adults boosted with an inactivated whole-cell mycobacterial vaccine.

Authors:  Charles F von Reyn; Lillian Mtei; Robert D Arbeit; Richard Waddell; Bernard Cole; Todd Mackenzie; Mecky Matee; Muhammad Bakari; Susan Tvaroha; Lisa V Adams; Charles R Horsburgh; Kisali Pallangyo
Journal:  AIDS       Date:  2010-03-13       Impact factor: 4.177

7.  'Even if they ask you to stand by a tree all day, you will have to do it (laughter)...!': community voices on the notion and practice of informed consent for biomedical research in developing countries.

Authors:  C S Molyneux; D R Wassenaar; N Peshu; K Marsh
Journal:  Soc Sci Med       Date:  2005-07       Impact factor: 4.634

8.  Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa.

Authors:  Laith J Abu-Raddad; Padmaja Patnaik; James G Kublin
Journal:  Science       Date:  2006-12-08       Impact factor: 47.728

Review 9.  Ethical perspective on malaria research for Africa.

Authors:  W L Kilama
Journal:  Acta Trop       Date:  2005-09       Impact factor: 3.112

10.  Provision of HIV treatment in HIV preventive vaccine trials: a developing country perspective.

Authors:  C Slack; M Stobie; C Milford; G Lindegger; D Wassenaar; A Strode; C Ijsselmuiden
Journal:  Soc Sci Med       Date:  2005-03       Impact factor: 4.634

View more
  10 in total

1.  The role of hospital-based cancer registries in low and middle income countries-The Nigerian Case Study.

Authors:  Elima E Jedy-Agba; Maria-Paula Curado; Emmanuel Oga; Modupeola O Samaila; Emmanuel R Ezeome; Christopher Obiorah; Olagoke O Erinomo; Ima-Obong A Ekanem; Cornelius Uka; Ahmed Mayun; Enoch A Afolayan; Popoola Abiodun; Babatunde J Olasode; Abidemi Omonisi; Theresa Otu; Patience Osinubi; Patrick Dakum; William Blattner; Clement A Adebamowo
Journal:  Cancer Epidemiol       Date:  2012-06-15       Impact factor: 2.984

Review 2.  Stakeholder Engagement in HIV Cure Research: Lessons Learned from Other HIV Interventions and the Way Forward.

Authors:  Ying-Ru Lo; Carissa Chu; Jintanat Ananworanich; Jean-Louis Excler; Joseph D Tucker
Journal:  AIDS Patient Care STDS       Date:  2015-05-18       Impact factor: 5.078

3.  Ethical considerations in malaria research proposal review: empirical evidence from 114 proposals submitted to an Ethics Committee in Thailand.

Authors:  Pornpimon Adams; Sukanya Prakobtham; Chanthima Limphattharacharoen; Pitchapa Vutikes; Srisin Khusmith; Krisana Pengsaa; Polrat Wilairatana; Jaranit Kaewkungwal
Journal:  Malar J       Date:  2015-09-14       Impact factor: 2.979

4.  Evaluating community engagement in global health research: the need for metrics.

Authors:  Kathleen M MacQueen; Anant Bhan; Janet Frohlich; Jessica Holzer; Jeremy Sugarman
Journal:  BMC Med Ethics       Date:  2015-07-01       Impact factor: 2.652

Review 5.  Ethical aspects of malaria control and research.

Authors:  Euzebiusz Jamrozik; Vânia de la Fuente-Núñez; Andreas Reis; Pascal Ringwald; Michael J Selgelid
Journal:  Malar J       Date:  2015-12-22       Impact factor: 2.979

6.  Ethical issues of informed consent in malaria research proposals submitted to a research ethics committee in Thailand: a retrospective document review.

Authors:  Pornpimon Adams; Sukanya Prakobtham; Chanthima Limpattaracharoen; Sumeth Suebtrakul; Pitchapa Vutikes; Srisin Khusmith; Polrat Wilairatana; Paul Adams; Jaranit Kaewkungwal
Journal:  BMC Med Ethics       Date:  2017-08-14       Impact factor: 2.652

7.  Willingness to participate in HIV vaccine trials among men who have sex with men in Chennai and Mumbai, India: a social ecological approach.

Authors:  Venkatesan Chakrapani; Peter A Newman; Neeti Singhal; Jhalak Jerajani; Murali Shunmugam
Journal:  PLoS One       Date:  2012-12-04       Impact factor: 3.240

8.  Improving ethical and participatory practice for marginalized populations in biomedical HIV prevention trials: lessons from Thailand.

Authors:  Dan Allman; Melissa Hope Ditmore; Karyn Kaplan
Journal:  PLoS One       Date:  2014-06-20       Impact factor: 3.240

Review 9.  Ethical Challenges and Lessons Learned During the Clinical Development of a Group A Meningococcal Conjugate Vaccine.

Authors:  Lionel Martellet; Samba O Sow; Aldiouma Diallo; Abraham Hodgson; Beate Kampmann; Siddhivinayak Hirve; Milagritos Tapia; Fadima Cheick Haidara; Assane Ndiaye; Bou Diarra; Patrick Odum Ansah; Adebayo Akinsola; Olubukola T Idoko; Richard A Adegbola; Ashish Bavdekar; Sanjay Juvekar; Simonetta Viviani; Godwin C Enwere; Elisa Marchetti; Julie Chaumont; Marie-Francoise Makadi; Flore Pallardy; Prasad S Kulkarni; Marie-Pierre Preziosi; F Marc LaForce
Journal:  Clin Infect Dis       Date:  2015-11-15       Impact factor: 9.079

10.  Using theory of change frameworks to develop evaluation strategies for research engagement: results of a pre-pilot study.

Authors:  Kathleen M MacQueen; Natalie T Eley; Mike Frick; Carol Hamilton
Journal:  J Int AIDS Soc       Date:  2018-10       Impact factor: 5.396

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.