| Literature DB >> 11861868 |
Ralph S Baric1, Boyd Yount, Lisa Lindesmith, Patrick R Harrington, Shermalyn R Greene, Fan-Chen Tseng, Nancy Davis, Robert E Johnston, David G Klapper, Christine L Moe.
Abstract
The Norwalk virus (NV) capsid protein was expressed using Venezuelan equine encephalitis virus replicon particles (VRP-NV1). VRP-NV1 infection resulted in large numbers of recombinant NV-like particles that were primarily cell associated and were indistinguishable from NV particles produced from baculoviruses. Mutations located in the N-terminal and P1 domains of the NV capsid protein ablated capsid self-assembly in mammalian cells.Entities:
Mesh:
Year: 2002 PMID: 11861868 PMCID: PMC135954 DOI: 10.1128/jvi.76.6.3023-3030.2002
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103