| Literature DB >> 9196224 |
K Y Green1, A Z Kapikian, J Valdesuso, S Sosnovtsev, J J Treanor, J F Lew.
Abstract
The Norwalk and Hawaii viruses are antigenically distinct members of the family Caliciviridae and are considered to be important etiologic agents of epidemic gastroenteritis, with most studies focusing on the role of Norwalk virus. To further investigate the importance of Hawaii virus, Hawaii virus-like particles (VLPs) were produced by expression of its capsid protein in the baculovirus system and these VLPs were used as the antigen in an enzyme-linked immunosorbent assay that was efficient in the detection of a serologic response to Hawaii virus. The ready availability of Hawaii VLPs should enable larger-scale epidemiological studies to further elucidate the importance of this agent.Entities:
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Year: 1997 PMID: 9196224 PMCID: PMC229872 DOI: 10.1128/jcm.35.7.1909-1914.1997
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948