Literature DB >> 11860079

An econometric analysis of screening and treatment of patients with suspected Chlamydia.

Manouche Tavakoli1, Ann-Marie Craig, Mo Malek.   

Abstract

Chlamydia trachomatis is probably the most common sexually transmitted disease in the Western industrialised countries with devastating consequences. However, it is an infection that can be so easily treated. There are over 50 million new cases occurring each year. In the United States chlamydia is seen as the most common and costly of the bacterial sexually transmitted diseases (STD), with approximately 4 million new cases occurring each year at an estimated total cost of $2.4 billion. The characteristic of this infection is its difficulty of detection that promotes its spread and making its prediction rather complex. Chlamydial infections are commonly asymptomatic or cause mild or non-specific symptoms and signs, which are not easily detected. Approximately 70% of women with endocervical infections and up to 50% of men with urethral infections are asymptomatic and thus not likely to seek medical care. Chlamydia has become known as the "silent epidemic". It is the more frequently identifiable single cause of pelvic inflammatory disease (PID), occurring in an estimated 15-40% of women. The primary objective of the study was to identify factors and quantify their contribution to the risk of being infected with Chlamydia and to construct an easy to use friendly method for early detection. The importance of developing some means of early detection is vital and previous studies suggest that selective screening might be one solution. A logit model was fitted to three broad variables: behavioural, patients' characteristics, and signs/symptoms noted by patient. The age of the women, the number of sexual partners over the past year, previous history of sexually transmitted disease, the use of barrier contraception and patients' and their partners' signs and symptoms were found to be among the most important variables. Such a model should allow patients who are in a high-risk category, allowing appropriate treatment.

Entities:  

Mesh:

Year:  2002        PMID: 11860079     DOI: 10.1023/a:1013249018847

Source DB:  PubMed          Journal:  Health Care Manag Sci        ISSN: 1386-9620


  13 in total

1.  Criteria for selective screening for Chlamydia trachomatis infection in women attending family planning clinics.

Authors:  H H Handsfield; L L Jasman; P L Roberts; V W Hanson; R L Kothenbeutel; W E Stamm
Journal:  JAMA       Date:  1986-04-04       Impact factor: 56.272

2.  Chlamydia trachomatis and sexually transmitted disease.

Authors:  D Taylor-Robinson
Journal:  BMJ       Date:  1994-01-15

Review 3.  New opportunities for Chlamydia prevention: applications of science to public health practice.

Authors:  S Hillis; C Black; J Newhall; C Walsh; S L Groseclose
Journal:  Sex Transm Dis       Date:  1995 May-Jun       Impact factor: 2.830

4.  Azithromycin in the treatment of sexually transmitted disease.

Authors:  O Steingrimsson; J H Olafsson; H Thorarinsson; R W Ryan; R B Johnson; R C Tilton
Journal:  J Antimicrob Chemother       Date:  1990-01       Impact factor: 5.790

5.  Epidemiologic and microbiologic correlates of Chlamydia trachomatis infection in sexual partnerships.

Authors:  T C Quinn; C Gaydos; M Shepherd; L Bobo; E W Hook; R Viscidi; A Rompalo
Journal:  JAMA       Date:  1996-12-04       Impact factor: 56.272

6.  A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males.

Authors:  A Nilsen; A Halsos; A Johansen; E Hansen; E Tørud; D Moseng; G Anestad; G Størvold
Journal:  Genitourin Med       Date:  1992-10

7.  A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group.

Authors:  D H Martin; T F Mroczkowski; Z A Dalu; J McCarty; R B Jones; S J Hopkins; R B Johnson
Journal:  N Engl J Med       Date:  1992-09-24       Impact factor: 91.245

8.  Compliance with antibiotic therapy for Chlamydia trachomatis and Neisseria gonorrhoeae.

Authors:  B P Katz; B W Zwickl; V A Caine; R B Jones
Journal:  Sex Transm Dis       Date:  1992 Nov-Dec       Impact factor: 2.830

9.  Prevention of pelvic inflammatory disease by screening for cervical chlamydial infection.

Authors:  D Scholes; A Stergachis; F E Heidrich; H Andrilla; K K Holmes; W E Stamm
Journal:  N Engl J Med       Date:  1996-05-23       Impact factor: 91.245

10.  Prevalence of Chlamydia trachomatis infection in women having cervical smear tests.

Authors:  J R Smith; J Murdoch; D Carrington; C E Frew; A J Dougall; H MacKinnon; D Baillie; D M Byford; C A Forrest; J A Davis
Journal:  BMJ       Date:  1991-01-12
View more
  2 in total

Review 1.  Vaccination against Chlamydia genital infection utilizing the murine C. muridarum model.

Authors:  Christina M Farris; Richard P Morrison
Journal:  Infect Immun       Date:  2010-11-15       Impact factor: 3.441

2.  Chlamydia trachomatis recombinant MOMP encapsulated in PLGA nanoparticles triggers primarily T helper 1 cellular and antibody immune responses in mice: a desirable candidate nanovaccine.

Authors:  Stacie J Fairley; Shree R Singh; Abebayehu N Yilma; Alain B Waffo; Praseetha Subbarayan; Saurabh Dixit; Murtada A Taha; Chino D Cambridge; Vida A Dennis
Journal:  Int J Nanomedicine       Date:  2013-05-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.