Literature DB >> 11854314

Proteotoxicity in the endoplasmic reticulum: lessons from the Akita diabetic mouse.

David Ron1.   

Abstract

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Year:  2002        PMID： 11854314      PMCID： PMC150880          DOI： 10.1172/JCI15020

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  30 in total

1.  Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.

Authors:  F Urano; X Wang; A Bertolotti; Y Zhang; P Chung; H P Harding; D Ron
Journal:  Science       Date:  2000-01-28       Impact factor: 47.728

2.  Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.

Authors:  A Bertolotti; Y Zhang; L M Hendershot; H P Harding; D Ron
Journal:  Nat Cell Biol       Date:  2000-06       Impact factor: 28.824

Review 3.  Tripartite management of unfolded proteins in the endoplasmic reticulum.

Authors:  K Mori
Journal:  Cell       Date:  2000-05-26       Impact factor: 41.582

4.  Translational control is required for the unfolded protein response and in vivo glucose homeostasis.

Authors:  D Scheuner; B Song; E McEwen; C Liu; R Laybutt; P Gillespie; T Saunders; S Bonner-Weir; R J Kaufman
Journal:  Mol Cell       Date:  2001-06       Impact factor: 17.970

5.  Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.

Authors:  C Y Liu; M Schröder; R J Kaufman
Journal:  J Biol Chem       Date:  2000-08-11       Impact factor: 5.157

6.  Compensatory responses in mice carrying a null mutation for Ins1 or Ins2.

Authors:  L Leroux; P Desbois; L Lamotte; B Duvillié; N Cordonnier; M Jackerott; J Jami; D Bucchini; R L Joshi
Journal:  Diabetes       Date:  2001-02       Impact factor: 9.461

7.  Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.

Authors:  T Nakagawa; H Zhu; N Morishima; E Li; J Xu; B A Yankner; J Yuan
Journal:  Nature       Date:  2000-01-06       Impact factor: 49.962

8.  Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.

Authors:  H P Harding; H Zeng; Y Zhang; R Jungries; P Chung; H Plesken; D D Sabatini; D Ron
Journal:  Mol Cell       Date:  2001-06       Impact factor: 17.970

9.  Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state.

Authors:  K D McCullough; J L Martindale; L O Klotz; T Y Aw; N J Holbrook
Journal:  Mol Cell Biol       Date:  2001-02       Impact factor: 4.272

10.  Perk is essential for translational regulation and cell survival during the unfolded protein response.

Authors:  H P Harding; Y Zhang; A Bertolotti; H Zeng; D Ron
Journal:  Mol Cell       Date:  2000-05       Impact factor: 17.970
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  78 in total

1.  Deciphering the hidden informational content of protein sequences: foldability of proinsulin hinges on a flexible arm that is dispensable in the mature hormone.

Authors:  Ming Liu; Qing-xin Hua; Shi-Quan Hu; Wenhua Jia; Yanwu Yang; Sunil Evan Saith; Jonathan Whittaker; Peter Arvan; Michael A Weiss
Journal:  J Biol Chem       Date:  2010-07-27       Impact factor: 5.157

2.  Endoplasmic reticulum overcrowding as a mechanism of beta-cell dysfunction in diabetes.

Authors:  F Despa
Journal:  Biophys J       Date:  2010-04-21       Impact factor: 4.033

3.  Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control.

Authors:  Alenka Copic; Mariana Dorrington; Silvere Pagant; Justine Barry; Marcus C S Lee; Indira Singh; John L Hartman; Elizabeth A Miller
Journal:  Genetics       Date:  2009-05-11       Impact factor: 4.562

4.  A general strategy for the bacterial expression of amyloidogenic peptides using BCL-XL-1/2 fusions.

Authors:  Isaac T Yonemoto; Malcolm R Wood; William E Balch; Jeffery W Kelly
Journal:  Protein Sci       Date:  2009-09       Impact factor: 6.725

Review 5.  The unfolded protein response and autophagy: herpesviruses rule!

Authors:  Dong Yun Lee; Jisook Lee; Bill Sugden
Journal:  J Virol       Date:  2008-09-10       Impact factor: 5.103

6.  Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK.

Authors:  Yukihiro Yamaguchi; Dennis Larkin; Roberto Lara-Lemus; Jose Ramos-Castañeda; Ming Liu; Peter Arvan
Journal:  J Biol Chem       Date:  2008-04-21       Impact factor: 5.157

7.  Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.

Authors:  Carlo Colombo; Ottavia Porzio; Ming Liu; Ornella Massa; Mario Vasta; Silvana Salardi; Luciano Beccaria; Carla Monciotti; Sonia Toni; Oluf Pedersen; Torben Hansen; Luca Federici; Roberta Pesavento; Francesco Cadario; Giorgio Federici; Paolo Ghirri; Peter Arvan; Dario Iafusco; Fabrizio Barbetti
Journal:  J Clin Invest       Date:  2008-06       Impact factor: 14.808

8.  A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.

Authors:  T Pearson; L D Shultz; J Lief; L Burzenski; B Gott; T Chase; O Foreman; A A Rossini; R Bottino; M Trucco; D L Greiner
Journal:  Diabetologia       Date:  2008-06-19       Impact factor: 10.122

9.  Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein family.

Authors:  Youhei Sohma; Qing-xin Hua; Ming Liu; Nelson B Phillips; Shi-Quan Hu; Jonathan Whittaker; Linda J Whittaker; Aubree Ng; Charles T Roberts; Peter Arvan; Stephen B H Kent; Michael A Weiss
Journal:  J Biol Chem       Date:  2009-12-03       Impact factor: 5.157

Review 10.  The role of the unfolded protein response in diabetes mellitus.

Authors:  Takao Iwawaki; Daisuke Oikawa
Journal:  Semin Immunopathol       Date:  2013-03-26       Impact factor: 9.623
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