Literature DB >> 11854030

DNA polymerase beta.

Haitham T Idriss1, Osama Al-Assar, Samuel H Wilson.   

Abstract

Mammalian DNA polymerase beta(beta-pol) is a single polypeptide chain enzyme of 39kDa. beta-pol has enzymatic activities appropriate for roles in base excision repair and other DNA metabolism events involving gap-filling DNA synthesis. Many crystal structures of beta-pol complexed with dNTP and DNA substrates have been solved, and mouse fibroblast cell lines deleted in the beta-pol gene have been examined. These approaches have enhanced our understanding of structural and functional aspects of beta-pol's role in protecting genomic DNA.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11854030     DOI： 10.1016/s1357-2725(01)00131-5

Source DB:  PubMed          Journal:  Int J Biochem Cell Biol        ISSN： 1357-2725            Impact factor:   5.085


  17 in total

1.  DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.

Authors:  Min Li; Wenqiao Zang; Yuanyuan Wang; Yuebai Li; Yunyun Ma; Na Wang; Yue Tang; Lulu Liu; Ziming Dong; Guoqiang Zhao
Journal:  Tumour Biol       Date:  2013-06-08

Review 2.  Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair.

Authors:  Lok Ming Tam; Nathan E Price; Yinsheng Wang
Journal:  Chem Res Toxicol       Date:  2020-02-07       Impact factor: 3.739

3.  DNA polymerase beta promoter mutations affect gene transcription, translation and the sensitivity of esophageal cancer cells to cisplatin treatment.

Authors:  Tao Wang; Wenqiao Zang; Yunyun Ma; Min Li; Xiaoyan Xuan; Na Wang; Rui Wu; Yuebai Li; Ziming Dong; Guoqiang Zhao
Journal:  Mol Biol Rep       Date:  2012-11-03       Impact factor: 2.316

Review 4.  Base excision repair: a critical player in many games.

Authors:  Susan S Wallace
Journal:  DNA Repair (Amst)       Date:  2014-04-26

5.  Mutation of DNA polymerase beta in esophageal carcinoma of different regions.

Authors:  Guo-Qiang Zhao; Tao Wang; Qin Zhao; Hong-Yan Yang; Xiao-Hui Tan; Zi-Ming Dong
Journal:  World J Gastroenterol       Date:  2005-08-14       Impact factor: 5.742

6.  DNA polymerase β mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.

Authors:  Min Li; Wenqiao Zang; Yuanyuan Wang; Yunyun Ma; Xiaoyan Xuan; Jimin Zhao; Lulu Liu; Ziming Dong; Guoqiang Zhao
Journal:  Tumour Biol       Date:  2014-01

7.  Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues.

Authors:  Matthew A Schaich; Mallory R Smith; Ashley S Cloud; Sean M Holloran; Bret D Freudenthal
Journal:  Chem Res Toxicol       Date:  2017-09-01       Impact factor: 3.739

8.  The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion.

Authors:  Jianpeng Wang; Keqin Ren; Javier Pérez; Alcino J Silva; Sandra Peña de Ortiz
Journal:  Learn Mem       Date:  2003 Nov-Dec       Impact factor: 2.460

9.  Dietary Calorie Restriction from Adulthood Through Old Age in Rats: Improved DNA Polymerase β and DNA Gap Repair Activity in Cortical Neurons.

Authors:  Umakanta Swain; V N Vyjayanti; T Harikrishna; S Mahipal; Kalluri Subba Rao
Journal:  Neurochem Res       Date:  2016-01-22       Impact factor: 3.996

10.  In situ analysis of repair processes for oxidative DNA damage in mammalian cells.

Authors:  Li Lan; Satoshi Nakajima; Yoshitsugu Oohata; Masashi Takao; Satoshi Okano; Mitsuko Masutani; Samuel H Wilson; Akira Yasui
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-13       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.