Literature DB >> 11850284

Penetration of rifampin through Staphylococcus epidermidis biofilms.

Zhilan Zheng1, Philip S Stewart.   

Abstract

Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria. Penetration was demonstrated by a simple diffusion cell bioassay and by transmission electron microscopic observation of antibiotic-affected cells at the distal edge of the biofilm.

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Year:  2002        PMID: 11850284      PMCID: PMC127480          DOI: 10.1128/AAC.46.3.900-903.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  23 in total

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  54 in total

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Review 10.  Rifampin as adjuvant treatment of Gram-positive bacterial infections: a systematic review of comparative clinical trials.

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