Literature DB >> 11848856

Bioisosterism: A Rational Approach in Drug Design.

George A. Patani1, Edmond J. LaVoie.   

Abstract

Year:  1996        PMID： 11848856     DOI： 10.1021/cr950066q

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  149 in total

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2.  Successful identification of key chemical structure modifications that lead to improved ADME profiles.

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Journal:  J Comput Aided Mol Des       Date:  2010-05-09       Impact factor: 3.686

3.  Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.

Authors:  Peter Wipf; Jingbo Xiao; Corey R J Stephenson
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4.  Anthracene-based inhibitors of dengue virus NS2B-NS3 protease.

Authors:  Suzanne M Tomlinson; Stanley J Watowich
Journal:  Antiviral Res       Date:  2010-12-23       Impact factor: 5.970

5.  Identification of target-specific bioisosteric fragments from ligand-protein crystallographic data.

Authors:  Elizabeth A Kennewell; Peter Willett; Pierre Ducrot; Claude Luttmann
Journal:  J Comput Aided Mol Des       Date:  2006-10-13       Impact factor: 3.686

6.  Automated molecule editing in molecular design.

Authors:  Peter W Kenny; Carlos A Montanari; Igor M Prokopczyk; Fernanda A Sala; Geraldo Rodrigues Sartori
Journal:  J Comput Aided Mol Des       Date:  2013-09-04       Impact factor: 3.686

7.  Modeling biophysical and biological properties from the characteristics of the molecular electron density, electron localization and delocalization matrices, and the electrostatic potential.

Authors:  Chérif F Matta
Journal:  J Comput Chem       Date:  2014-04-29       Impact factor: 3.376

8.  Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Authors:  Bo-Liang Deng; Yujie Zhao; Tracy L Hartman; Karen Watson; Robert W Buckheit; Christophe Pannecouque; Erik De Clercq; Mark Cushman
Journal:  Eur J Med Chem       Date:  2008-09-19       Impact factor: 6.514

Review 9.  1,2,4-Triazolo[1,5-a]pyrimidines in drug design.

Authors:  Killian Oukoloff; Bobby Lucero; Karol R Francisco; Kurt R Brunden; Carlo Ballatore
Journal:  Eur J Med Chem       Date:  2019-01-14       Impact factor: 6.514

10.  Design, Synthesis, and Identification of Silicon Incorporated Oxazolidinone Antibiotics with Improved Brain Exposure.

Authors:  B Seetharamsingh; Remya Ramesh; Santoshkumar S Dange; Pankaj V Khairnar; Smita Singhal; Dilip Upadhyay; Sridhar Veeraraghavan; Srikant Viswanadha; Swaroop Vakkalanka; D Srinivasa Reddy
Journal:  ACS Med Chem Lett       Date:  2015-10-26       Impact factor: 4.345
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