| Literature DB >> 118466 |
L Carlsson, F Markey, I Blikstad, T Persson, U Lindberg.
Abstract
The effect of thrombin stimulation on actin organization in human platelets has been analyzed by using the DNase I inhibition assay, which is selective for unpolymerized and filamentous actin. The results provide biochemical evidence for the suggestion that stimulation leads to rapid polymerization of actin. The measurements also reveal changes in the polymerization state of actin occurring after cell lysis. These changes are influenced by the concentration of free calcium in the extracts.Entities:
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Year: 1979 PMID: 118466 PMCID: PMC411867 DOI: 10.1073/pnas.76.12.6376
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205