Literature DB >> 11839607

A model for odour thresholds.

Michael H Abraham1, Joëlle M R Gola, J Enrique Cometto-Muniz, William S Cain.   

Abstract

Odour detection thresholds, that we have previously obtained, have been analysed by a general equation for selective transport. It is shown that such selective transport can account for some 77% of the total effect. The remainder is due to a specific size effect, that might involve odour-binding proteins, and a specific effect for aldehydes and carboxylic acids. Our analysis raises the question of whether selective transport is physically separable from the specific effects of receptor activation. The model predicts a chemical cut-off in odour detection along any homologous series.

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Year:  2002        PMID: 11839607     DOI: 10.1093/chemse/27.2.95

Source DB:  PubMed          Journal:  Chem Senses        ISSN: 0379-864X            Impact factor:   3.160


  15 in total

1.  An algorithm for 353 odor detection thresholds in humans.

Authors:  Michael H Abraham; Ricardo Sánchez-Moreno; J Enrique Cometto-Muñiz; William S Cain
Journal:  Chem Senses       Date:  2011-10-04       Impact factor: 3.160

2.  Odor frequency and odor annoyance. Part I: assessment of frequency, intensity and hedonic tone of environmental odors in the field.

Authors:  Kirsten Sucker; Ralf Both; Michael Bischoff; Rainer Guski; Gerhard Winneke
Journal:  Int Arch Occup Environ Health       Date:  2007-10-12       Impact factor: 3.015

3.  Cutoff in detection of eye irritation from vapors of homologous carboxylic acids and aliphatic aldehydes.

Authors:  J E Cometto-Muñiz; W S Cain; M H Abraham; R Sánchez-Moreno
Journal:  Neuroscience       Date:  2007-01-30       Impact factor: 3.590

4.  Structure-activity relationships on the odor detectability of homologous carboxylic acids by humans.

Authors:  J Enrique Cometto-Muñiz; Michael H Abraham
Journal:  Exp Brain Res       Date:  2010-10-08       Impact factor: 1.972

5.  Odor detection by humans of lineal aliphatic aldehydes and helional as gauged by dose-response functions.

Authors:  J Enrique Cometto-Muñiz; Michael H Abraham
Journal:  Chem Senses       Date:  2010-02-26       Impact factor: 3.160

6.  Concentration-detection functions for the odor of homologous n-acetate esters.

Authors:  J Enrique Cometto-Muñiz; William S Cain; Michael H Abraham; Javier Gil-Lostes
Journal:  Physiol Behav       Date:  2008-10-08

7.  Olfactory psychometric functions for homologous 2-ketones.

Authors:  J Enrique Cometto-Muñiz; Michael H Abraham
Journal:  Behav Brain Res       Date:  2009-02-21       Impact factor: 3.332

8.  The biological and toxicological activity of gases and vapors.

Authors:  Michael H Abraham; Ricardo Sánchez-Moreno; Javier Gil-Lostes; William E Acree; J Enrique Cometto-Muñiz; William S Cain
Journal:  Toxicol In Vitro       Date:  2009-11-12       Impact factor: 3.500

9.  Concentration-detection functions for eye irritation evoked by homologous n-alcohols and acetates approaching a cut-off point.

Authors:  J Enrique Cometto-Muñiz; William S Cain; Michael H Abraham; Ricardo Sánchez-Moreno
Journal:  Exp Brain Res       Date:  2007-05-15       Impact factor: 1.972

10.  Olfactory detectability of homologous n-alkylbenzenes as reflected by concentration-detection functions in humans.

Authors:  J E Cometto-Muñiz; M H Abraham
Journal:  Neuroscience       Date:  2009-03-20       Impact factor: 3.590

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