Literature DB >> 11839559

Neuropathological verisimilitude in animal models of Alzheimer's disease: key to elucidating neurodegenerative pathways and identifying new targets for drug discovery.

John Q Trojanowski1.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 11839559      PMCID: PMC1850634          DOI: 10.1016/S0002-9440(10)64858-4

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


× No keyword cloud information.
  24 in total

1.  Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice.

Authors:  A L Phinney; T Deller; M Stalder; M E Calhoun; M Frotscher; B Sommer; M Staufenbiel; M Jucker
Journal:  J Neurosci       Date:  1999-10-01       Impact factor: 6.167

Review 2.  Treatment of Alzheimer's disease.

Authors:  R Mayeux; M Sano
Journal:  N Engl J Med       Date:  1999-11-25       Impact factor: 91.245

Review 3.  "Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders.

Authors:  J Q Trojanowski; V M Lee
Journal:  Ann N Y Acad Sci       Date:  2000       Impact factor: 5.691

4.  Plaque-associated alpha-synuclein (NACP) pathology in aged transgenic mice expressing amyloid precursor protein.

Authors:  F Yang; K Uéda; P Chen; K H Ashe; G M Cole
Journal:  Brain Res       Date:  2000-01-24       Impact factor: 3.252

5.  Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

Authors:  D Praticò; K Uryu; S Leight; J Q Trojanoswki; V M Lee
Journal:  J Neurosci       Date:  2001-06-15       Impact factor: 6.167

6.  Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Authors:  J Lewis; D W Dickson; W L Lin; L Chisholm; A Corral; G Jones; S H Yen; N Sahara; L Skipper; D Yager; C Eckman; J Hardy; M Hutton; E McGowan
Journal:  Science       Date:  2001-08-24       Impact factor: 47.728

7.  Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice.

Authors:  W C Benzing; J R Wujek; E K Ward; D Shaffer; K H Ashe; S G Younkin; K R Brunden
Journal:  Neurobiol Aging       Date:  1999 Nov-Dec       Impact factor: 4.673

8.  Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice.

Authors:  F C Bronfman; D Moechars; F Van Leuven
Journal:  Neurobiol Dis       Date:  2000-06       Impact factor: 5.996

Review 9.  Synucleinopathies: clinical and pathological implications.

Authors:  J E Galvin; V M Lee; J Q Trojanowski
Journal:  Arch Neurol       Date:  2001-02

10.  Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Authors:  T Kawarabayashi; L H Younkin; T C Saido; M Shoji; K H Ashe; S G Younkin
Journal:  J Neurosci       Date:  2001-01-15       Impact factor: 6.167

View more
  1 in total

1.  Cortical neurons transgenic for human Abeta40 or Abeta42 have similar vulnerability to apoptosis despite their different amyloidogenic properties.

Authors:  Najeeb A Shiwany; Jun Xie; Qing Guo
Journal:  Int J Clin Exp Pathol       Date:  2008-11-26
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.