Literature DB >> 11834679

Airway hyperresponsiveness and calcium handling by smooth muscle: a "deeper look".

Krishnan Parameswaran1, Luke J Janssen, Paul M O'Byrne.   

Abstract

We propose that abnormal calcium handling by the airway smooth muscle may be an important determinant of airway hyperresponsiveness. The amplitude, frequency, or localization of Ca(2+) oscillations in the smooth muscle may determine the degree of airway sensitivity and reactivity, which are characteristic features of asthma.

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Year:  2002        PMID： 11834679     DOI： 10.1378/chest.121.2.621

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  7 in total

Review 1.  Effect of aging on cellular mechanotransduction.

Authors:  Miaozong Wu; Jacqueline Fannin; Kevin M Rice; Bin Wang; Eric R Blough
Journal:  Ageing Res Rev       Date:  2009-11-20       Impact factor: 10.895

2.  Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.

Authors:  Katharina Mahn; Stuart J Hirst; Sun Ying; Mark R Holt; Paul Lavender; Oluwaseun O Ojo; Leonard Siew; David E Simcock; Clare G McVicker; Varsha Kanabar; Vladimir A Snetkov; Brian J O'Connor; Charlotta Karner; David J Cousins; Patricia Macedo; K Fan Chung; Christopher J Corrigan; Jeremy P T Ward; Tak H Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-16       Impact factor: 11.205

3.  The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro.

Authors:  Miao Li; Yun-Xiao Shang; Bing Wei; Yun-Gang Yang
Journal:  J Inflamm (Lond)       Date:  2011-07-21       Impact factor: 4.981

4.  The pivotal role of airway smooth muscle in asthma pathophysiology.

Authors:  Annaïg Ozier; Benoit Allard; Imane Bara; Pierre-Olivier Girodet; Thomas Trian; Roger Marthan; Patrick Berger
Journal:  J Allergy (Cairo)       Date:  2011-12-11

5.  Ca2+-signaling in airway smooth muscle cells is altered in T-bet knock-out mice.

Authors:  Albrecht Bergner; Julia Kellner; Anita Kemp da Silva; Fernando Gamarra; Rudolf M Huber
Journal:  Respir Res       Date:  2006-02-23

Review 6.  Muscarinic receptor signaling in the pathophysiology of asthma and COPD.

Authors:  Reinoud Gosens; Johan Zaagsma; Herman Meurs; Andrew J Halayko
Journal:  Respir Res       Date:  2006-05-09

7.  STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma.

Authors:  Martin T Johnson; Ping Xin; J Cory Benson; Trayambak Pathak; Vonn Walter; Scott M Emrich; Ryan E Yoast; Xuexin Zhang; Gaoyuan Cao; Reynold A Panettieri; Mohamed Trebak
Journal:  Proc Natl Acad Sci U S A       Date:  2022-01-04       Impact factor: 11.205
  7 in total

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